2pny

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[[Image:2pny.jpg|left|200px]]
 
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{{Structure
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==Structure of Human Isopentenyl-diphosphate Delta-isomerase 2==
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|PDB= 2pny |SIZE=350|CAPTION= <scene name='initialview01'>2pny</scene>, resolution 1.81&Aring;
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<StructureSection load='2pny' size='340' side='right'caption='[[2pny]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>
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<table><tr><td colspan='2'>[[2pny]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PNY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PNY FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Isopentenyl-diphosphate_Delta-isomerase Isopentenyl-diphosphate Delta-isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.3.2 5.3.3.2] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81&#8491;</td></tr>
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|GENE= IDI2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pny FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pny OCA], [https://pdbe.org/2pny PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pny RCSB], [https://www.ebi.ac.uk/pdbsum/2pny PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pny ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pny FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pny OCA], [http://www.ebi.ac.uk/pdbsum/2pny PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pny RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/IDI2_HUMAN IDI2_HUMAN] Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pn/2pny_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pny ConSurf].
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<div style="clear:both"></div>
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'''Structure of Human Isopentenyl-diphosphate Delta-isomerase 2'''
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==See Also==
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*[[Isopentenyl-diphosphate delta-isomerase|Isopentenyl-diphosphate delta-isomerase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2PNY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PNY OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Isopentenyl-diphosphate Delta-isomerase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Arrowsmith CH]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Bochkarev A]]
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[[Category: Bochkarev, A.]]
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[[Category: Butler-Cole C]]
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[[Category: Butler-Cole, C.]]
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[[Category: Davis T]]
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[[Category: Davis, T.]]
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[[Category: Dhe-Paganon S]]
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[[Category: Dhe-Paganon, S.]]
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[[Category: Edwards AM]]
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[[Category: Edwards, A M.]]
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[[Category: Sundstrom M]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Walker JR]]
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[[Category: Sundstrom, M.]]
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[[Category: Weigelt J]]
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[[Category: Walker, J R.]]
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[[Category: Weigelt, J.]]
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[[Category: carotenoid biosynthesis]]
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[[Category: cholesterol biosynthesis]]
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[[Category: isomerase]]
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[[Category: isoprene biosynthesis]]
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[[Category: lipid synthesis]]
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[[Category: peroxisome]]
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[[Category: sgc]]
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[[Category: steroid biosynthesis]]
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[[Category: sterol biosynthesis]]
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[[Category: structural genomic]]
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[[Category: structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:38:34 2008''
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Current revision

Structure of Human Isopentenyl-diphosphate Delta-isomerase 2

PDB ID 2pny

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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