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6efw

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==Crystal structure of a YjeF family protein from Cryptococcus neoformans var. grubii serotype A==
==Crystal structure of a YjeF family protein from Cryptococcus neoformans var. grubii serotype A==
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<StructureSection load='6efw' size='340' side='right' caption='[[6efw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='6efw' size='340' side='right'caption='[[6efw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6efw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EFW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EFW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6efw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptococcus_neoformans_var._grubii_H99 Cryptococcus neoformans var. grubii H99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EFW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6EFW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ATP-dependent_NAD(P)H-hydrate_dehydratase ATP-dependent NAD(P)H-hydrate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.93 4.2.1.93] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6efw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6efw OCA], [http://pdbe.org/6efw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6efw RCSB], [http://www.ebi.ac.uk/pdbsum/6efw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6efw ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6efw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6efw OCA], [https://pdbe.org/6efw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6efw RCSB], [https://www.ebi.ac.uk/pdbsum/6efw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6efw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/J9VIT7_CRYNH J9VIT7_CRYNH]] Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.[HAMAP-Rule:MF_03157]
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[https://www.uniprot.org/uniprot/J9VIT7_CRYNH J9VIT7_CRYNH] Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.[HAMAP-Rule:MF_03157]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Structural genomic]]
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[[Category: Cryptococcus neoformans var. grubii H99]]
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[[Category: Atp]]
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[[Category: Large Structures]]
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[[Category: Cryptococcus neoforman]]
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[[Category: Lyase]]
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[[Category: Ssgcid]]
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[[Category: Yjef]]
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Current revision

Crystal structure of a YjeF family protein from Cryptococcus neoformans var. grubii serotype A

PDB ID 6efw

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