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5omv

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Current revision (16:55, 13 December 2023) (edit) (undo)
 
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==Ternary complex of 9N DNA polymerase in the replicative state with two metal ions in the active site==
==Ternary complex of 9N DNA polymerase in the replicative state with two metal ions in the active site==
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<StructureSection load='5omv' size='340' side='right' caption='[[5omv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='5omv' size='340' side='right'caption='[[5omv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5omv]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thes9 Thes9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OMV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5omv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_sp._9oN-7 Thermococcus sp. 9oN-7] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OMV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.003&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol, polA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=103799 THES9])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5omv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5omv OCA], [https://pdbe.org/5omv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5omv RCSB], [https://www.ebi.ac.uk/pdbsum/5omv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5omv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5omv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5omv OCA], [http://pdbe.org/5omv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5omv RCSB], [http://www.ebi.ac.uk/pdbsum/5omv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5omv ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPOL_THES9 DPOL_THES9]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[DNA polymerase|DNA polymerase]]
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Large Structures]]
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[[Category: Thes9]]
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[[Category: Synthetic construct]]
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[[Category: Betz, K]]
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[[Category: Thermococcus sp. 9oN-7]]
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[[Category: Diederichs, K]]
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[[Category: Betz K]]
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[[Category: Marx, A]]
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[[Category: Diederichs K]]
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[[Category: Dna polymerase]]
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[[Category: Marx A]]
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[[Category: Ternary complex]]
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[[Category: Transferase]]
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[[Category: Triphosphate]]
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Current revision

Ternary complex of 9N DNA polymerase in the replicative state with two metal ions in the active site

PDB ID 5omv

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