2v91

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==STRUCTURE OF STRICTOSIDINE SYNTHASE IN COMPLEX WITH STRICTOSIDINE==
==STRUCTURE OF STRICTOSIDINE SYNTHASE IN COMPLEX WITH STRICTOSIDINE==
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<StructureSection load='2v91' size='340' side='right' caption='[[2v91]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
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<StructureSection load='2v91' size='340' side='right'caption='[[2v91]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2v91]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ophioxylon_serpentinum Ophioxylon serpentinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V91 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V91 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2v91]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rauvolfia_serpentina Rauvolfia serpentina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V91 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V91 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S55:METHYL+(2S,3R,4S)-3-ETHYL-2-(BETA-D-GLUCOPYRANOSYLOXY)-4-[(1S)-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLIN-1-YLMETHYL]-3,4-DIHYDRO-2H-PYRAN-5-CARBOXYLATE'>S55</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.01&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fpc|2fpc]], [[2fp8|2fp8]], [[2fp9|2fp9]], [[2fpb|2fpb]], [[2vaq|2vaq]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=S55:METHYL+(2S,3R,4S)-3-ETHYL-2-(BETA-D-GLUCOPYRANOSYLOXY)-4-[(1S)-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLIN-1-YLMETHYL]-3,4-DIHYDRO-2H-PYRAN-5-CARBOXYLATE'>S55</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Strictosidine_synthase Strictosidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.3.2 4.3.3.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v91 OCA], [https://pdbe.org/2v91 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v91 RCSB], [https://www.ebi.ac.uk/pdbsum/2v91 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v91 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v91 OCA], [http://pdbe.org/2v91 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v91 RCSB], [http://www.ebi.ac.uk/pdbsum/2v91 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v91 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/STSY_RAUSE STSY_RAUSE]] Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis.
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[https://www.uniprot.org/uniprot/STSY_RAUSE STSY_RAUSE] Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/2v91_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/2v91_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ophioxylon serpentinum]]
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[[Category: Large Structures]]
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[[Category: Strictosidine synthase]]
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[[Category: Rauvolfia serpentina]]
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[[Category: Barleben, L]]
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[[Category: Barleben L]]
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[[Category: Loris, E A]]
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[[Category: Loris EA]]
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[[Category: Panjikar, S]]
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[[Category: Panjikar S]]
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[[Category: Ruppert, M]]
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[[Category: Ruppert M]]
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[[Category: Stoeckigt, J]]
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[[Category: Stoeckigt J]]
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[[Category: Unger, M]]
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[[Category: Unger M]]
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[[Category: Alkaloid metabolism]]
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[[Category: Glycoprotein]]
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[[Category: Lyase]]
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[[Category: Six bladed beta propeller fold]]
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[[Category: Str1]]
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[[Category: Synthase]]
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[[Category: Vacuole]]
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Current revision

STRUCTURE OF STRICTOSIDINE SYNTHASE IN COMPLEX WITH STRICTOSIDINE

PDB ID 2v91

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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