2ux9

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==Crystal structure of the T. thermophilus dodecin R65A mutant==
==Crystal structure of the T. thermophilus dodecin R65A mutant==
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<StructureSection load='2ux9' size='340' side='right' caption='[[2ux9]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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<StructureSection load='2ux9' size='340' side='right'caption='[[2ux9]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ux9]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UX9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UX9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ux9]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UX9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UX9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2v19|2v19]], [[2v21|2v21]], [[2v18|2v18]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ux9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ux9 OCA], [http://pdbe.org/2ux9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ux9 RCSB], [http://www.ebi.ac.uk/pdbsum/2ux9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ux9 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ux9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ux9 OCA], [https://pdbe.org/2ux9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ux9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ux9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ux9 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DODEC_THET8 DODEC_THET8] May function as storage protein that sequesters various flavins and other cofactors, thereby protecting the cell against undesirable reactions mediated by the free cofactors. Binds and sequesters FMN, FAD, lumiflavin and lumichrome, and can also bind coenzyme A.<ref>PMID:17855371</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thet8]]
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[[Category: Large Structures]]
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[[Category: Essen, L O]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Meissner, B]]
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[[Category: Essen L-O]]
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[[Category: Flavoprotein]]
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[[Category: Meissner B]]

Current revision

Crystal structure of the T. thermophilus dodecin R65A mutant

PDB ID 2ux9

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