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5yed

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==Crystal structure of LokiProfilin1==
==Crystal structure of LokiProfilin1==
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<StructureSection load='5yed' size='340' side='right' caption='[[5yed]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='5yed' size='340' side='right'caption='[[5yed]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5yed]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YED OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YED FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5yed]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lokiarchaeum_sp._GC14_75 Lokiarchaeum sp. GC14_75]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YED OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YED FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yed FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yed OCA], [http://pdbe.org/5yed PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yed RCSB], [http://www.ebi.ac.uk/pdbsum/5yed PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yed ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yed FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yed OCA], [https://pdbe.org/5yed PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yed RCSB], [https://www.ebi.ac.uk/pdbsum/5yed PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yed ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PROF1_LOKSG PROF1_LOKSG] Binds to actin and affects the structure of the cytoskeleton. At high concentrations inhibits spontaneous rabbit actin nucleation. This strongly suggests this archaea has a profilin-regulated actin system, and actin-type genes can be identified in this organism.<ref>PMID:30283132</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Akil, C]]
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[[Category: Large Structures]]
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[[Category: Robinson, R C]]
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[[Category: Lokiarchaeum sp. GC14_75]]
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[[Category: Actin]]
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[[Category: Akil C]]
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[[Category: Archaea]]
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[[Category: Robinson RC]]
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[[Category: Structural protein]]
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Current revision

Crystal structure of LokiProfilin1

PDB ID 5yed

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