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2w3u

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==formate complex of the Ni-Form of E.coli deformylase==
==formate complex of the Ni-Form of E.coli deformylase==
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<StructureSection load='2w3u' size='340' side='right' caption='[[2w3u]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
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<StructureSection load='2w3u' size='340' side='right'caption='[[2w3u]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2w3u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W3U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W3U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2w3u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W3U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W3U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1def|1def]], [[1lru|1lru]], [[1bs8|1bs8]], [[1bsk|1bsk]], [[2vhm|2vhm]], [[1bs7|1bs7]], [[2ai8|2ai8]], [[2def|2def]], [[1icj|1icj]], [[1bs4|1bs4]], [[1bs5|1bs5]], [[1bsz|1bsz]], [[2w3t|2w3t]], [[1dff|1dff]], [[1g2a|1g2a]], [[1g27|1g27]], [[1bs6|1bs6]], [[1dtf|1dtf]], [[1bsj|1bsj]], [[2dtf|2dtf]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Formylmethionine_deformylase Formylmethionine deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.31 3.5.1.31] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w3u OCA], [https://pdbe.org/2w3u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w3u RCSB], [https://www.ebi.ac.uk/pdbsum/2w3u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w3u ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w3u OCA], [http://pdbe.org/2w3u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w3u RCSB], [http://www.ebi.ac.uk/pdbsum/2w3u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w3u ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DEF_ECOLI DEF_ECOLI]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
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[https://www.uniprot.org/uniprot/DEF_ECOLI DEF_ECOLI] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Formylmethionine deformylase]]
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[[Category: Large Structures]]
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[[Category: Hinrichs, W]]
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[[Category: Hinrichs W]]
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[[Category: Ngo, Y H.T]]
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[[Category: Ngo YHT]]
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[[Category: Palm, G J]]
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[[Category: Palm GJ]]
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[[Category: Formate complex]]
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[[Category: Hydrolase]]
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[[Category: Nickel]]
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Current revision

formate complex of the Ni-Form of E.coli deformylase

PDB ID 2w3u

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