6cuv

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==Engineered Holo TrpB from Pyrococcus furiosus, PfTrpB7E6==
==Engineered Holo TrpB from Pyrococcus furiosus, PfTrpB7E6==
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<StructureSection load='6cuv' size='340' side='right' caption='[[6cuv]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
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<StructureSection load='6cuv' size='340' side='right'caption='[[6cuv]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6cuv]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CUV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CUV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6cuv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CUV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CUV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptophan_synthase Tryptophan synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.20 4.2.1.20] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cuv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cuv OCA], [https://pdbe.org/6cuv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cuv RCSB], [https://www.ebi.ac.uk/pdbsum/6cuv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cuv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cuv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cuv OCA], [http://pdbe.org/6cuv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cuv RCSB], [http://www.ebi.ac.uk/pdbsum/6cuv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cuv ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TRPB1_PYRFU TRPB1_PYRFU]] The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine (By similarity).
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[https://www.uniprot.org/uniprot/TRPB1_PYRFU TRPB1_PYRFU] The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6cuv" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6cuv" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Tryptophan synthase]]
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[[Category: Large Structures]]
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[[Category: Arnold, F H]]
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[[Category: Pyrococcus furiosus DSM 3638]]
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[[Category: Boville, C E]]
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[[Category: Arnold FH]]
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[[Category: Buller, A R]]
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[[Category: Boville CE]]
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[[Category: Scheele, R A]]
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[[Category: Buller AR]]
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[[Category: Internal aldimine]]
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[[Category: Scheele RA]]
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[[Category: Lyase]]
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Current revision

Engineered Holo TrpB from Pyrococcus furiosus, PfTrpB7E6

PDB ID 6cuv

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