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2qhu

From Proteopedia

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[[Image:2qhu.jpg|left|200px]]
 
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{{Structure
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==Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B==
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|PDB= 2qhu |SIZE=350|CAPTION= <scene name='initialview01'>2qhu</scene>, resolution 1.900&Aring;
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<StructureSection load='2qhu' size='340' side='right'caption='[[2qhu]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Oya+Binding+Site+For+Residue+A+1001'>AC1</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=OYA:OCTANAL'>OYA</scene>
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<table><tr><td colspan='2'>[[2qhu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QHU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QHU FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OYA:OCTANAL'>OYA</scene></td></tr>
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|GENE= TTC 1746 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2qhs|2qhs]], [[2qht|2qht]], [[2qhv|2qhv]]</div></td></tr>
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|DOMAIN=
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTC 1746 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
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|RELATEDENTRY=[[2qhs|2QHS]], [[2qht|2QHT]], [[2qhv|2QHV]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qhu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qhu OCA], [https://pdbe.org/2qhu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qhu RCSB], [https://www.ebi.ac.uk/pdbsum/2qhu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qhu ProSAT]</span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qhu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qhu OCA], [http://www.ebi.ac.uk/pdbsum/2qhu PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2qhu RCSB]</span>
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</table>
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}}
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== Function ==
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[[https://www.uniprot.org/uniprot/LIPB_THET8 LIPB_THET8]] Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity).
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'''Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B'''
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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==About this Structure==
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<jmolCheckbox>
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2QHU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QHU OCA].
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qh/2qhu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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==Reference==
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<text>to colour the structure by Evolutionary Conservation</text>
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Structural basis of octanoic acid recognition by lipoate-protein ligase B., Kim do J, Lee SJ, Kim HS, Kim KH, Lee HH, Yoon HJ, Suh SW, Proteins. 2008 Mar;70(4):1620-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18076036 18076036]
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</jmolCheckbox>
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[[Category: Single protein]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qhu ConSurf].
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[[Category: Thermus thermophilus]]
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<div style="clear:both"></div>
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[[Category: Kim, D J.]]
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__TOC__
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[[Category: Kim, H S.]]
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</StructureSection>
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[[Category: Kim, K H.]]
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[[Category: Large Structures]]
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[[Category: Lee, H H.]]
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[[Category: Thet8]]
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[[Category: Lee, S J.]]
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[[Category: Kim, D J]]
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[[Category: Suh, S W.]]
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[[Category: Kim, H S]]
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[[Category: Yoon, H J.]]
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[[Category: Kim, K H]]
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[[Category: globular protein]]
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[[Category: Lee, H H]]
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[[Category: transferase]]
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[[Category: Lee, S J]]
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[[Category: Suh, S W]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:49:30 2008''
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[[Category: Yoon, H J]]
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[[Category: Globular protein]]
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[[Category: Transferase]]

Current revision

Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B

PDB ID 2qhu

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