6hrl

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m (Protected "6hrl" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6hrl is ON HOLD
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==Crystal structure of the Kelch domain of human KLHL17==
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<StructureSection load='6hrl' size='340' side='right'caption='[[6hrl]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6hrl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HRL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6HRL FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6hrl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hrl OCA], [https://pdbe.org/6hrl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6hrl RCSB], [https://www.ebi.ac.uk/pdbsum/6hrl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6hrl ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KLH17_HUMAN KLH17_HUMAN] Substrate-recognition component of some cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(KLHL17) mediates the ubiquitination and subsequenct degradation of GLUR6. May play a role in the actin-based neuronal function (By similarity).
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Authors: Chen, Z., Williams, E., Sorrell, F.J., Newman, J.A., Shrestha, L., Burgess-Brown, N., von Delft, F., Arrowsmith, F., Edwards, C.H., Bountra, C., Bullock, A.N.
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==See Also==
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*[[Kelch-like protein 3D structures|Kelch-like protein 3D structures]]
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Description: Crystal structure of the Kelch domain of human KLHL17
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__TOC__
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[[Category: Unreleased Structures]]
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</StructureSection>
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[[Category: Burgess-Brown, N]]
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[[Category: Homo sapiens]]
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[[Category: Shrestha, L]]
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[[Category: Large Structures]]
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[[Category: Newman, J.A]]
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[[Category: Arrowsmith F]]
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[[Category: Chen, Z]]
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[[Category: Bountra C]]
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[[Category: Williams, E]]
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[[Category: Bullock AN]]
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[[Category: Edwards, C.H]]
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[[Category: Burgess-Brown N]]
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[[Category: Arrowsmith, F]]
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[[Category: Chen Z]]
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[[Category: Von Delft, F]]
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[[Category: Edwards CH]]
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[[Category: Bountra, C]]
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[[Category: Newman JA]]
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[[Category: Bullock, A.N]]
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[[Category: Shrestha L]]
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[[Category: Sorrell, F.J]]
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[[Category: Sorrell FJ]]
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[[Category: Williams E]]
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[[Category: Von Delft F]]

Current revision

Crystal structure of the Kelch domain of human KLHL17

PDB ID 6hrl

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