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2qlt

From Proteopedia

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[[Image:2qlt.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of an isoform of DL-glycerol-3-phosphatase, Rhr2p, from Saccharomyces cerevisiae==
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|PDB= 2qlt |SIZE=350|CAPTION= <scene name='initialview01'>2qlt</scene>, resolution 1.60&Aring;
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<StructureSection load='2qlt' size='340' side='right'caption='[[2qlt]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[2qlt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QLT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QLT FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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|GENE= GPP1, RHR2, YIL053W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0637 COG0637]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qlt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qlt OCA], [https://pdbe.org/2qlt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qlt RCSB], [https://www.ebi.ac.uk/pdbsum/2qlt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qlt ProSAT], [https://www.topsan.org/Proteins/MCSG/2qlt TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qlt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qlt OCA], [http://www.ebi.ac.uk/pdbsum/2qlt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2qlt RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/GPP1_YEAST GPP1_YEAST] Major isoform of glycerol-1-phosphate phosphohydrolase involved in glycerol biosynthesis. Plays a role in osmoadaptation and required for adaptation to anaerobic conditions.<ref>PMID:8662716</ref> <ref>PMID:11058591</ref> <ref>PMID:15113568</ref> <ref>PMID:16358322</ref> <ref>PMID:18438874</ref>
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== Evolutionary Conservation ==
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'''Crystal structure of an isoform of DL-glycerol-3-phosphatase, Rhr2p, from Saccharomyces cerevisiae'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ql/2qlt_consurf.spt"</scriptWhenChecked>
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2QLT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QLT OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qlt ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Edwards A]]
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[[Category: Edwards, A.]]
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[[Category: Evdokimova E]]
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[[Category: Evdokimova, E.]]
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[[Category: Joachimiak A]]
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[[Category: Joachimiak, A.]]
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[[Category: Kudritska M]]
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[[Category: Kudritska, M.]]
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[[Category: Savchenko A]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Tan K]]
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[[Category: Savchenko, A.]]
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[[Category: Tan, K.]]
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[[Category: apc7326]]
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[[Category: dl-glycerol-3-phosphatase isoform]]
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[[Category: hydrolase]]
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[[Category: mcsg]]
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[[Category: midwest center for structural genomic]]
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[[Category: protein structure initiative]]
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[[Category: psi-2]]
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[[Category: rhr2p]]
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[[Category: saccharomyces cerevisiae]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:50:39 2008''
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Current revision

Crystal structure of an isoform of DL-glycerol-3-phosphatase, Rhr2p, from Saccharomyces cerevisiae

PDB ID 2qlt

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