6mk9
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6mk9 is ON HOLD until Paper Publication Authors: Yedidi, R.S., Hayashi, H., Das, D., Mitsuya, H. Description: X-ray crystal structure of darunavir-...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==X-ray crystal structure of darunavir-resistant-P51 HIV-1 protease in complex with GRL-121== | |
| - | + | <StructureSection load='6mk9' size='340' side='right'caption='[[6mk9]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6mk9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MK9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MK9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7O7:(3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl+{(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate'>7O7</scene></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mk9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mk9 OCA], [https://pdbe.org/6mk9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mk9 RCSB], [https://www.ebi.ac.uk/pdbsum/6mk9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mk9 ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[ | + | == Function == |
| - | [[Category: Das | + | [https://www.uniprot.org/uniprot/A0A4P8EW36_HV1 A0A4P8EW36_HV1] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Human immunodeficiency virus 1]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Das D]] | ||
| + | [[Category: Hayashi H]] | ||
| + | [[Category: Mitsuya H]] | ||
| + | [[Category: Yedidi RS]] | ||
Current revision
X-ray crystal structure of darunavir-resistant-P51 HIV-1 protease in complex with GRL-121
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