5jmx

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==Crystal Structure of BcII metallo-beta-lactamase in complex with DZ-305==
==Crystal Structure of BcII metallo-beta-lactamase in complex with DZ-305==
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<StructureSection load='5jmx' size='340' side='right' caption='[[5jmx]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
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<StructureSection load='5jmx' size='340' side='right'caption='[[5jmx]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5jmx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_14579 Atcc 14579]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JMX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JMX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5jmx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JMX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JMX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DZ5:(2Z)-3-(4-FLUOROPHENYL)-2-SULFANYLPROP-2-ENOIC+ACID'>DZ5</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.44&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blm ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1396 ATCC 14579])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DZ5:(2Z)-3-(4-FLUOROPHENYL)-2-SULFANYLPROP-2-ENOIC+ACID'>DZ5</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jmx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jmx OCA], [https://pdbe.org/5jmx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jmx RCSB], [https://www.ebi.ac.uk/pdbsum/5jmx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jmx ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jmx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jmx OCA], [http://pdbe.org/5jmx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jmx RCSB], [http://www.ebi.ac.uk/pdbsum/5jmx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jmx ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BLA2_BACCE BLA2_BACCE]] Can hydrolyze carbapenem compounds.
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[https://www.uniprot.org/uniprot/BLA2_BACCE BLA2_BACCE] Can hydrolyze carbapenem compounds.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Beta-lactamase|Beta-lactamase]]
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 14579]]
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[[Category: Bacillus cereus]]
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
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[[Category: Brem, J]]
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[[Category: Brem J]]
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[[Category: McDonough, M A]]
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[[Category: McDonough MA]]
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[[Category: Schofield, C J]]
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[[Category: Schofield CJ]]
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[[Category: Stepanovs, D]]
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[[Category: Stepanovs D]]
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[[Category: Zhang, D]]
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[[Category: Zhang D]]
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[[Category: Antimicrobial resistance]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Metallo beta lactamase]]
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Current revision

Crystal Structure of BcII metallo-beta-lactamase in complex with DZ-305

PDB ID 5jmx

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