2qqe

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[[Image:2qqe.gif|left|200px]]
 
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{{Structure
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==Thymidine Kinase from Thermotoga Maritima in complex with Thymidine==
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|PDB= 2qqe |SIZE=350|CAPTION= <scene name='initialview01'>2qqe</scene>, resolution 1.90&Aring;
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<StructureSection load='2qqe' size='340' side='right'caption='[[2qqe]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=THM:THYMIDINE'>THM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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<table><tr><td colspan='2'>[[2qqe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QQE FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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|GENE= tdk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=THM:THYMIDINE'>THM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qqe OCA], [https://pdbe.org/2qqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qqe RCSB], [https://www.ebi.ac.uk/pdbsum/2qqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qqe ProSAT]</span></td></tr>
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|RELATEDENTRY=[[2qpo|2QPO]], [[2qq0|2QQ0]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qqe OCA], [http://www.ebi.ac.uk/pdbsum/2qqe PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2qqe RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/KITH_THEMA KITH_THEMA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qq/2qqe_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qqe ConSurf].
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<div style="clear:both"></div>
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'''Thymidine Kinase from Thermotoga Maritima in complex with Thymidine'''
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==See Also==
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*[[Thymidine kinase 3D structures|Thymidine kinase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2QQE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QQE OCA].
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Thymidine kinase]]
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[[Category: Konrad M]]
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[[Category: Konrad, M.]]
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[[Category: Lavie A]]
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[[Category: Lavie, A.]]
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[[Category: Lichter J]]
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[[Category: Lichter, J.]]
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[[Category: Lutz S]]
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[[Category: Lutz, S.]]
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[[Category: Segura-Pena D]]
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[[Category: Segura-Pena, D.]]
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[[Category: Trani M]]
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[[Category: Trani, M.]]
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[[Category: atp-binding]]
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[[Category: close conformation]]
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[[Category: cytoplasm]]
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[[Category: dna synthesis]]
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[[Category: kinase]]
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[[Category: nucleotide-binding]]
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[[Category: tmtk in complex with thymidine]]
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[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:52:05 2008''
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Current revision

Thymidine Kinase from Thermotoga Maritima in complex with Thymidine

PDB ID 2qqe

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