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5zxh
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The structure of MT189-tubulin complex== |
| + | <StructureSection load='5zxh' size='340' side='right'caption='[[5zxh]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5zxh]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus], [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZXH FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9LX:2-(6-fluoro-3-{[(4-methoxyphenyl)methyl]amino}imidazo[1,2-a]pyridin-2-yl)phenol'>9LX</scene>, <scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zxh OCA], [https://pdbe.org/5zxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zxh RCSB], [https://www.ebi.ac.uk/pdbsum/5zxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zxh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | ||
| - | + | ==See Also== | |
| - | + | *[[Stathmin-4 3D structures|Stathmin-4 3D structures]] | |
| - | + | *[[Tubulin 3D Structures|Tubulin 3D Structures]] | |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Bos taurus]] |
| - | [[Category: | + | [[Category: Gallus gallus]] |
| - | [[Category: Chen | + | [[Category: Large Structures]] |
| - | [[Category: Yang | + | [[Category: Rattus norvegicus]] |
| + | [[Category: Sus scrofa]] | ||
| + | [[Category: Chen Q]] | ||
| + | [[Category: Li ZP]] | ||
| + | [[Category: Meng T]] | ||
| + | [[Category: Wang YX]] | ||
| + | [[Category: Yang JL]] | ||
Current revision
The structure of MT189-tubulin complex
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Categories: Bos taurus | Gallus gallus | Large Structures | Rattus norvegicus | Sus scrofa | Chen Q | Li ZP | Meng T | Wang YX | Yang JL
