5zxh

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'''Unreleased structure'''
 
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The entry 5zxh is ON HOLD until Paper Publication
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==The structure of MT189-tubulin complex==
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<StructureSection load='5zxh' size='340' side='right'caption='[[5zxh]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5zxh]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus], [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZXH FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9LX:2-(6-fluoro-3-{[(4-methoxyphenyl)methyl]amino}imidazo[1,2-a]pyridin-2-yl)phenol'>9LX</scene>, <scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zxh OCA], [https://pdbe.org/5zxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zxh RCSB], [https://www.ebi.ac.uk/pdbsum/5zxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zxh ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
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Authors: Li, Z.P., Wang, Y.X., Meng, T., Yang, J.L., Chen, Q.
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==See Also==
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*[[Stathmin-4 3D structures|Stathmin-4 3D structures]]
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Description: The structure of MT189-tubulin complex
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*[[Tubulin 3D Structures|Tubulin 3D Structures]]
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[[Category: Unreleased Structures]]
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__TOC__
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[[Category: Wang, Y.X]]
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</StructureSection>
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[[Category: Meng, T]]
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[[Category: Bos taurus]]
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[[Category: Li, Z.P]]
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[[Category: Gallus gallus]]
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[[Category: Chen, Q]]
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[[Category: Large Structures]]
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[[Category: Yang, J.L]]
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[[Category: Rattus norvegicus]]
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[[Category: Sus scrofa]]
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[[Category: Chen Q]]
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[[Category: Li ZP]]
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[[Category: Meng T]]
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[[Category: Wang YX]]
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[[Category: Yang JL]]

Current revision

The structure of MT189-tubulin complex

PDB ID 5zxh

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