2qux

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[[Image:2qux.jpg|left|200px]]
 
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{{Structure
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==PP7 coat protein dimer in complex with RNA hairpin==
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|PDB= 2qux |SIZE=350|CAPTION= <scene name='initialview01'>2qux</scene>, resolution 2.44&Aring;
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<StructureSection load='2qux' size='340' side='right'caption='[[2qux]], [[Resolution|resolution]] 2.44&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
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<table><tr><td colspan='2'>[[2qux]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_phage_PP7 Pseudomonas phage PP7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QUX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QUX FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.44&#8491;</td></tr>
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|GENE= PP7 coat protein ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12023 Pseudomonas phage PP7])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qux OCA], [https://pdbe.org/2qux PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qux RCSB], [https://www.ebi.ac.uk/pdbsum/2qux PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qux ProSAT]</span></td></tr>
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|RELATEDENTRY=[[1dwn|1DWN]], [[2qud|2QUD]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qux FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qux OCA], [http://www.ebi.ac.uk/pdbsum/2qux PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2qux RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/Q38062_BPPP7 Q38062_BPPP7]
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<div style="background-color:#fffaf0;">
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'''PP7 coat protein dimer in complex with RNA hairpin'''
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== Publication Abstract from PubMed ==
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==Overview==
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The cocrystal structure of the PP7 bacteriophage coat protein in complex with its translational operator identifies a distinct mode of sequence-specific RNA recognition when compared to the well-characterized MS2 coat protein-RNA complex. The structure reveals the molecular basis of the PP7 coat protein's ability to selectively bind its cognate RNA, and it demonstrates that the conserved beta-sheet surface is a flexible architecture that can evolve to recognize diverse RNA hairpins.
The cocrystal structure of the PP7 bacteriophage coat protein in complex with its translational operator identifies a distinct mode of sequence-specific RNA recognition when compared to the well-characterized MS2 coat protein-RNA complex. The structure reveals the molecular basis of the PP7 coat protein's ability to selectively bind its cognate RNA, and it demonstrates that the conserved beta-sheet surface is a flexible architecture that can evolve to recognize diverse RNA hairpins.
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==About this Structure==
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Structural basis for the coevolution of a viral RNA-protein complex.,Chao JA, Patskovsky Y, Almo SC, Singer RH Nat Struct Mol Biol. 2008 Jan;15(1):103-5. Epub 2007 Dec 9. PMID:18066080<ref>PMID:18066080</ref>
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2QUX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_phage_pp7 Pseudomonas phage pp7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QUX OCA].
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==Reference==
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Structural basis for the coevolution of a viral RNA-protein complex., Chao JA, Patskovsky Y, Almo SC, Singer RH, Nat Struct Mol Biol. 2008 Jan;15(1):103-5. Epub 2007 Dec 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18066080 18066080]
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[[Category: Pseudomonas phage pp7]]
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[[Category: Single protein]]
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[[Category: Chao, J A.]]
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[[Category: bacteriophage coat protein]]
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[[Category: capsid protein]]
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[[Category: rna-protein complex]]
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[[Category: structural protein/rna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:53:33 2008''
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2qux" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Pseudomonas phage PP7]]
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[[Category: Chao JA]]

Current revision

PP7 coat protein dimer in complex with RNA hairpin

PDB ID 2qux

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