6iie
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of human diacylglycerol kinase alpha EF-hand domains bound to Ca2+== | |
+ | <StructureSection load='6iie' size='340' side='right'caption='[[6iie]], [[Resolution|resolution]] 2.14Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[6iie]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IIE FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.142Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6iie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iie OCA], [https://pdbe.org/6iie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6iie RCSB], [https://www.ebi.ac.uk/pdbsum/6iie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6iie ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/DGKA_HUMAN DGKA_HUMAN] Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. | ||
- | + | ==See Also== | |
- | + | *[[Diacylglycerol kinase 3D structures|Diacylglycerol kinase 3D structures]] | |
- | + | __TOC__ | |
- | [[Category: | + | </StructureSection> |
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Iwamoto T]] | ||
+ | [[Category: Murata T]] | ||
+ | [[Category: Sakamoto T]] | ||
+ | [[Category: Sakane F]] | ||
+ | [[Category: Suzuki K]] | ||
+ | [[Category: Takahashi D]] |
Current revision
Crystal structure of human diacylglycerol kinase alpha EF-hand domains bound to Ca2+
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Categories: Homo sapiens | Large Structures | Iwamoto T | Murata T | Sakamoto T | Sakane F | Suzuki K | Takahashi D