5z8x

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==Crystal structure of a synaptic protein==
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==Crystal structure of human LRRTM2==
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<StructureSection load='5z8x' size='340' side='right' caption='[[5z8x]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
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<StructureSection load='5z8x' size='340' side='right'caption='[[5z8x]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5z8x]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z8X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Z8X FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5z8x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z8X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Z8X FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5z8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z8x OCA], [http://pdbe.org/5z8x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z8x RCSB], [http://www.ebi.ac.uk/pdbsum/5z8x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z8x ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5z8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z8x OCA], [https://pdbe.org/5z8x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5z8x RCSB], [https://www.ebi.ac.uk/pdbsum/5z8x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5z8x ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LRRT2_HUMAN LRRT2_HUMAN]] Involved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B (By similarity).
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[https://www.uniprot.org/uniprot/LRRT2_HUMAN LRRT2_HUMAN] Involved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Fukai, S]]
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[[Category: Homo sapiens]]
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[[Category: Yamagata, A]]
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[[Category: Large Structures]]
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[[Category: Cell adhesion]]
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[[Category: Fukai S]]
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[[Category: Leucine-rich repeat]]
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[[Category: Yamagata A]]
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[[Category: Synapse]]
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[[Category: Synaptic organizer]]
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Current revision

Crystal structure of human LRRTM2

PDB ID 5z8x

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