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6cig
From Proteopedia
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==CRYSTAL STRUCTURE ANALYSIS OF SELENOMETHIONINE SUBSTITUTED ISOFLAVONE O-METHYLTRANSFERASE== | ==CRYSTAL STRUCTURE ANALYSIS OF SELENOMETHIONINE SUBSTITUTED ISOFLAVONE O-METHYLTRANSFERASE== | ||
| - | <StructureSection load='6cig' size='340' side='right' caption='[[6cig]], [[Resolution|resolution]] 1.65Å' scene=''> | + | <StructureSection load='6cig' size='340' side='right'caption='[[6cig]], [[Resolution|resolution]] 1.65Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6cig]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6cig]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Alfalfa Alfalfa]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1fpx 1fpx]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CIG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CIG FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=T3A:N-(TRIS(HYDROXYMETHYL)METHYL)-3-AMINOPROPANESULFONIC+ACID'>T3A</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=T3A:N-(TRIS(HYDROXYMETHYL)METHYL)-3-AMINOPROPANESULFONIC+ACID'>T3A</scene></td></tr> |
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Isoflavone_7-O-methyltransferase Isoflavone 7-O-methyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.150 2.1.1.150] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cig OCA], [https://pdbe.org/6cig PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cig RCSB], [https://www.ebi.ac.uk/pdbsum/6cig PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cig ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/7OMT8_MEDSA 7OMT8_MEDSA]] Transfers a methyl group to 7-hydroxyls of the isoflavones daidzein, genistein and 6,7,4'-trihydroxyisoflavone. Can also methylate (+)6a-hydroxymaackiain with lower efficiency. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Alfalfa]] | [[Category: Alfalfa]] | ||
[[Category: Isoflavone 7-O-methyltransferase]] | [[Category: Isoflavone 7-O-methyltransferase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Dixon, R A]] | [[Category: Dixon, R A]] | ||
[[Category: Kowiel, M]] | [[Category: Kowiel, M]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Noel, J P]] | [[Category: Noel, J P]] | ||
[[Category: Porebski, P J]] | [[Category: Porebski, P J]] | ||
[[Category: Shabalin, I G]] | [[Category: Shabalin, I G]] | ||
[[Category: Zubieta, C]] | [[Category: Zubieta, C]] | ||
| - | [[Category: Nysgrc]] | ||
| - | [[Category: Psi-biology]] | ||
[[Category: S-adenosyl-l-homocysteine complex]] | [[Category: S-adenosyl-l-homocysteine complex]] | ||
[[Category: Selenomethionine]] | [[Category: Selenomethionine]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Current revision
CRYSTAL STRUCTURE ANALYSIS OF SELENOMETHIONINE SUBSTITUTED ISOFLAVONE O-METHYLTRANSFERASE
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