5ce1
From Proteopedia
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==Crystal Structure of Serine protease Hepsin in complex with Inhibitor== | ==Crystal Structure of Serine protease Hepsin in complex with Inhibitor== | ||
| - | <StructureSection load='5ce1' size='340' side='right' caption='[[5ce1]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='5ce1' size='340' side='right'caption='[[5ce1]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5ce1]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5ce1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CE1 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=50K:2-[6-(1-HYDROXYCYCLOHEXYL)PYRIDIN-2-YL]-1H-INDOLE-5-CARBOXIMIDAMIDE'>50K</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ce1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ce1 OCA], [https://pdbe.org/5ce1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ce1 RCSB], [https://www.ebi.ac.uk/pdbsum/5ce1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ce1 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/HEPS_HUMAN HEPS_HUMAN] Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL.<ref>PMID:21875933</ref> <ref>PMID:15839837</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Anirudha | + | [[Category: Anirudha L]] |
| - | [[Category: Anita | + | [[Category: Anita RC]] |
| - | [[Category: Rao | + | [[Category: Rao KN]] |
| - | [[Category: Sangeetha | + | [[Category: Sangeetha R]] |
| - | [[Category: Subramnay | + | [[Category: Subramnay H]] |
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Current revision
Crystal Structure of Serine protease Hepsin in complex with Inhibitor
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