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2rcy
From Proteopedia
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| - | [[Image:2rcy.jpg|left|200px]] | ||
| - | + | ==Crystal structure of Plasmodium falciparum pyrroline carboxylate reductase (MAL13P1.284) with NADP bound== | |
| - | + | <StructureSection load='2rcy' size='340' side='right'caption='[[2rcy]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | | | + | <table><tr><td colspan='2'>[[2rcy]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RCY FirstGlance]. <br> |
| - | | | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAL13P1.284 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Pyrroline-5-carboxylate_reductase Pyrroline-5-carboxylate reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.2 1.5.1.2] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rcy OCA], [https://pdbe.org/2rcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rcy RCSB], [https://www.ebi.ac.uk/pdbsum/2rcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rcy ProSAT]</span></td></tr> | |
| - | + | </table> | |
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rc/2rcy_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rcy ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Pyrroline-5-carboxylate reductase|Pyrroline-5-carboxylate reductase]] | |
| - | + | __TOC__ | |
| - | == | + | </StructureSection> |
| - | + | [[Category: Large Structures]] | |
| - | [[Category: | + | [[Category: Plaf7]] |
[[Category: Pyrroline-5-carboxylate reductase]] | [[Category: Pyrroline-5-carboxylate reductase]] | ||
| - | + | [[Category: Amani, M]] | |
| - | [[Category: Amani, M | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Arrowsmith, C H | + | [[Category: Artz, J D]] |
| - | [[Category: Artz, J D | + | [[Category: Bochkarev, A]] |
| - | [[Category: Bochkarev, A | + | [[Category: Edwards, A M]] |
| - | [[Category: Edwards, A M | + | [[Category: Hassanali, A]] |
| - | [[Category: Hassanali, A | + | [[Category: Hui, R]] |
| - | [[Category: Hui, R | + | [[Category: Khuu, C]] |
| - | [[Category: Khuu, C | + | [[Category: Kozieradzki, I]] |
| - | [[Category: Kozieradzki, I | + | [[Category: Lew, J]] |
| - | [[Category: Lew, J | + | [[Category: Lin, Y H]] |
| - | [[Category: Lin, | + | [[Category: Ren, H]] |
| - | [[Category: Ren, H | + | [[Category: Structural genomic]] |
| - | [[Category: | + | [[Category: Schapira, M]] |
| - | [[Category: Schapira, M | + | [[Category: Sun, X]] |
| - | [[Category: Sun, X | + | [[Category: Sundstrom, M]] |
| - | [[Category: Sundstrom, M | + | [[Category: Wasney, G]] |
| - | [[Category: Wasney, G | + | [[Category: Weigelt, J]] |
| - | [[Category: Weigelt, J | + | [[Category: Wernimont, A K]] |
| - | [[Category: Wernimont, A K | + | [[Category: Zhao, Y]] |
| - | [[Category: Zhao, Y | + | [[Category: Malaria]] |
| - | [[Category: | + | [[Category: Oxidoreductase]] |
| - | [[Category: | + | [[Category: Pyrroline reductase]] |
| - | [[Category: | + | [[Category: Sgc]] |
| - | [[Category: | + | |
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Current revision
Crystal structure of Plasmodium falciparum pyrroline carboxylate reductase (MAL13P1.284) with NADP bound
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Categories: Large Structures | Plaf7 | Pyrroline-5-carboxylate reductase | Amani, M | Arrowsmith, C H | Artz, J D | Bochkarev, A | Edwards, A M | Hassanali, A | Hui, R | Khuu, C | Kozieradzki, I | Lew, J | Lin, Y H | Ren, H | Structural genomic | Schapira, M | Sun, X | Sundstrom, M | Wasney, G | Weigelt, J | Wernimont, A K | Zhao, Y | Malaria | Oxidoreductase | Pyrroline reductase | Sgc
