2yxd

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==Crystal Structure of Cobalamin biosynthesis precorrin 8W decarboxylase (cbiT)==
==Crystal Structure of Cobalamin biosynthesis precorrin 8W decarboxylase (cbiT)==
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<StructureSection load='2yxd' size='340' side='right' caption='[[2yxd]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='2yxd' size='340' side='right'caption='[[2yxd]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2yxd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YXD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2yxd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_DSM_2661 Methanocaldococcus jannaschii DSM 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YXD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cbiT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxd OCA], [https://pdbe.org/2yxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yxd RCSB], [https://www.ebi.ac.uk/pdbsum/2yxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yxd ProSAT], [https://www.topsan.org/Proteins/RSGI/2yxd TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxd OCA], [http://pdbe.org/2yxd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yxd RCSB], [http://www.ebi.ac.uk/pdbsum/2yxd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yxd ProSAT], [http://www.topsan.org/Proteins/RSGI/2yxd TOPSAN]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CBIT_METJA CBIT_METJA]] Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7 (By similarity).
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[https://www.uniprot.org/uniprot/CBIT_METJA CBIT_METJA] Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7 (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yx/2yxd_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yx/2yxd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Metja]]
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[[Category: Large Structures]]
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[[Category: Bessho, Y]]
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[[Category: Methanocaldococcus jannaschii DSM 2661]]
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[[Category: Padmanabhan, B]]
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[[Category: Bessho Y]]
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[[Category: Structural genomic]]
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[[Category: Padmanabhan B]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Methyltransferase superfamily]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of Cobalamin biosynthesis precorrin 8W decarboxylase (cbiT)

PDB ID 2yxd

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