2z0y

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==Crystal structure of TTHA0657-SAM complex==
==Crystal structure of TTHA0657-SAM complex==
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<StructureSection load='2z0y' size='340' side='right' caption='[[2z0y]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='2z0y' size='340' side='right'caption='[[2z0y]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2z0y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z0Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z0Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2z0y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z0Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z0Y FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z0y OCA], [http://pdbe.org/2z0y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z0y RCSB], [http://www.ebi.ac.uk/pdbsum/2z0y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2z0y ProSAT], [http://www.topsan.org/Proteins/RSGI/2z0y TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z0y OCA], [https://pdbe.org/2z0y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z0y RCSB], [https://www.ebi.ac.uk/pdbsum/2z0y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z0y ProSAT], [https://www.topsan.org/Proteins/RSGI/2z0y TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q5SKI6_THET8 Q5SKI6_THET8]] Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity).[PIRNR:PIRNR015601]
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[https://www.uniprot.org/uniprot/Q5SKI6_THET8 Q5SKI6_THET8] Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity).[PIRNR:PIRNR015601]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z0/2z0y_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z0/2z0y_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
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[[Category: Large Structures]]
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[[Category: Kuramitsu, S]]
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[[Category: Thermus thermophilus]]
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[[Category: Murayama, K]]
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[[Category: Kuramitsu S]]
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[[Category: Structural genomic]]
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[[Category: Murayama K]]
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[[Category: Shirouzu, M]]
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[[Category: Shirouzu M]]
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[[Category: Terada, T]]
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[[Category: Terada T]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Transferase]]
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[[Category: Trefoil knot]]
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Current revision

Crystal structure of TTHA0657-SAM complex

PDB ID 2z0y

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