2yzd

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==Crystal structure of uricase from Arthrobacter globiformis in complex with 8-azaxanthin (inhibitor)==
==Crystal structure of uricase from Arthrobacter globiformis in complex with 8-azaxanthin (inhibitor)==
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<StructureSection load='2yzd' size='340' side='right' caption='[[2yzd]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
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<StructureSection load='2yzd' size='340' side='right'caption='[[2yzd]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2yzd]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YZD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2yzd]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YZD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AZA:8-AZAXANTHINE'>AZA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.24&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vay|1vay]], [[1vax|1vax]], [[1uox|1uox]], [[2yzb|2yzb]], [[2yzc|2yzc]], [[2yze|2yze]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZA:8-AZAXANTHINE'>AZA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Factor_independent_urate_hydroxylase Factor independent urate hydroxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.3.3 1.7.3.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yzd OCA], [https://pdbe.org/2yzd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yzd RCSB], [https://www.ebi.ac.uk/pdbsum/2yzd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yzd ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yzd OCA], [http://pdbe.org/2yzd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yzd RCSB], [http://www.ebi.ac.uk/pdbsum/2yzd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yzd ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/URIC_ARTGO URIC_ARTGO]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yz/2yzd_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yz/2yzd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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==See Also==
==See Also==
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*[[Urate Oxidase|Urate Oxidase]]
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*[[Urate oxidase 3D structures|Urate oxidase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arthrobacter globiformis]]
[[Category: Arthrobacter globiformis]]
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[[Category: Factor independent urate hydroxylase]]
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[[Category: Large Structures]]
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[[Category: Hoque, M M]]
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[[Category: Hoque MM]]
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[[Category: Hossain, M T]]
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[[Category: Hossain MT]]
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[[Category: Juan, E C.M]]
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[[Category: Juan ECM]]
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[[Category: Sekiguchi, T]]
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[[Category: Sekiguchi T]]
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[[Category: Suzuki, K]]
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[[Category: Suzuki K]]
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[[Category: Takenaka, A]]
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[[Category: Takenaka A]]
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[[Category: 8-azaxanthin]]
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[[Category: Oxidoreductase]]
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[[Category: Uricase]]
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Current revision

Crystal structure of uricase from Arthrobacter globiformis in complex with 8-azaxanthin (inhibitor)

PDB ID 2yzd

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