2z17

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==Crystal sturcture of PDZ domain from human Pleckstrin homology, Sec7==
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==Crystal structure of PDZ domain from human Pleckstrin homology, Sec7==
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<StructureSection load='2z17' size='340' side='right' caption='[[2z17]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='2z17' size='340' side='right'caption='[[2z17]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2z17]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z17 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z17 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2z17]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z17 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z17 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z17 OCA], [http://pdbe.org/2z17 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z17 RCSB], [http://www.ebi.ac.uk/pdbsum/2z17 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2z17 ProSAT], [http://www.topsan.org/Proteins/RSGI/2z17 TOPSAN]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z17 OCA], [https://pdbe.org/2z17 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z17 RCSB], [https://www.ebi.ac.uk/pdbsum/2z17 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z17 ProSAT], [https://www.topsan.org/Proteins/RSGI/2z17 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CYTIP_HUMAN CYTIP_HUMAN]] By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.
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[https://www.uniprot.org/uniprot/CYTIP_HUMAN CYTIP_HUMAN] By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Kishishita, S]]
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[[Category: Large Structures]]
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[[Category: Murayama, K]]
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[[Category: Kishishita S]]
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[[Category: Nishino, A]]
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[[Category: Murayama K]]
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[[Category: Structural genomic]]
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[[Category: Nishino A]]
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[[Category: Shirouzu, M]]
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[[Category: Shirouzu M]]
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[[Category: Terada, T]]
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[[Category: Terada T]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Coiled coil]]
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[[Category: Cytoplasm]]
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[[Category: Membrane]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Pdz domain]]
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[[Category: Polymorphism]]
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[[Category: Protein binding]]
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[[Category: Rsgi]]
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Current revision

Crystal structure of PDZ domain from human Pleckstrin homology, Sec7

PDB ID 2z17

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