2zw2

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==Crystal Structure of Formylglycinamide Ribonucleotide Amidotransferase III from SULFOLOBUS TOKODAII (STPURS)==
==Crystal Structure of Formylglycinamide Ribonucleotide Amidotransferase III from SULFOLOBUS TOKODAII (STPURS)==
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<StructureSection load='2zw2' size='340' side='right' caption='[[2zw2]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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<StructureSection load='2zw2' size='340' side='right'caption='[[2zw2]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2zw2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dsm_16993 Dsm 16993]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZW2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZW2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2zw2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii Sulfurisphaera tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZW2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">purS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=111955 DSM 16993])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoribosylformylglycinamidine_synthase Phosphoribosylformylglycinamidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.5.3 6.3.5.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zw2 OCA], [https://pdbe.org/2zw2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zw2 RCSB], [https://www.ebi.ac.uk/pdbsum/2zw2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zw2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zw2 OCA], [http://pdbe.org/2zw2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zw2 RCSB], [http://www.ebi.ac.uk/pdbsum/2zw2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zw2 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/F9VNF4_SULTO F9VNF4_SULTO] Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.[HAMAP-Rule:MF_01926]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Dsm 16993]]
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[[Category: Large Structures]]
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[[Category: Phosphoribosylformylglycinamidine synthase]]
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[[Category: Sulfurisphaera tokodaii]]
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[[Category: Baba, S]]
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[[Category: Baba S]]
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[[Category: Kawai, G]]
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[[Category: Kawai G]]
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[[Category: Kumasaka, T]]
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[[Category: Kumasaka T]]
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[[Category: Kuramitsu, S]]
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[[Category: Kuramitsu S]]
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[[Category: Masui, R]]
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[[Category: Masui R]]
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[[Category: Nakagawa, N]]
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[[Category: Nakagawa N]]
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[[Category: Okada, K]]
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[[Category: Okada K]]
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[[Category: Sampei, G]]
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[[Category: Sampei G]]
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[[Category: Suzuki, S]]
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[[Category: Suzuki S]]
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[[Category: Tamura, S]]
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[[Category: Tamura S]]
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[[Category: Ligase]]
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[[Category: Purine metabolism]]
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Current revision

Crystal Structure of Formylglycinamide Ribonucleotide Amidotransferase III from SULFOLOBUS TOKODAII (STPURS)

PDB ID 2zw2

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