2rhg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (22:29, 26 March 2025) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2rhg.jpg|left|200px]]
 
-
{{Structure
+
==Tryptophan synthase complexed with IGP, pH 7.0, internal aldimine==
-
|PDB= 2rhg |SIZE=350|CAPTION= <scene name='initialview01'>2rhg</scene>, resolution 2.00&Aring;
+
<StructureSection load='2rhg' size='340' side='right'caption='[[2rhg]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=IGP:INDOLE-3-GLYCEROL+PHOSPHATE'>IGP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5&#39;-PHOSPHATE'>PLP</scene>
+
<table><tr><td colspan='2'>[[2rhg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RHG FirstGlance]. <br>
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptophan_synthase Tryptophan synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.20 4.2.1.20] </span>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
|GENE= trpA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=602 Salmonella typhimurium]), trpB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=602 Salmonella typhimurium])
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IGP:INDOLE-3-GLYCEROL+PHOSPHATE'>IGP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
-
|DOMAIN=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rhg OCA], [https://pdbe.org/2rhg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rhg RCSB], [https://www.ebi.ac.uk/pdbsum/2rhg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rhg ProSAT]</span></td></tr>
-
|RELATEDENTRY=
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rhg OCA], [http://www.ebi.ac.uk/pdbsum/2rhg PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2rhg RCSB]</span>
+
== Function ==
-
}}
+
[https://www.uniprot.org/uniprot/TRPA_SALTY TRPA_SALTY] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rh/2rhg_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rhg ConSurf].
 +
<div style="clear:both"></div>
-
'''Tryptophan synthase complexed with IGP, pH 7.0, internal aldimine'''
+
==See Also==
-
 
+
*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
2RHG is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RHG OCA].
+
[[Category: Large Structures]]
-
[[Category: Protein complex]]
+
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-
[[Category: Salmonella typhimurium]]
+
[[Category: Barends T]]
-
[[Category: Tryptophan synthase]]
+
[[Category: Kulik V]]
-
[[Category: Barends, T.]]
+
[[Category: Schlichting I]]
-
[[Category: Kulik, V.]]
+
-
[[Category: Schlichting, I.]]
+
-
[[Category: allosteric enzyme]]
+
-
[[Category: amino-acid biosynthesis]]
+
-
[[Category: aminoacid biosynthesis]]
+
-
[[Category: aromatic amino acid biosynthesis]]
+
-
[[Category: carbon-oxygen lyase]]
+
-
[[Category: lyase]]
+
-
[[Category: pyridoxal phosphate]]
+
-
[[Category: tryptophan biosynthesis]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:00:25 2008''
+

Current revision

Tryptophan synthase complexed with IGP, pH 7.0, internal aldimine

PDB ID 2rhg

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2rhg"
Personal tools