2rhs

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:22, 21 February 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2rhs.jpg|left|200px]]
 
-
{{Structure
+
==PheRS from Staphylococcus haemolyticus- rational protein engineering and inhibitor studies==
-
|PDB= 2rhs |SIZE=350|CAPTION= <scene name='initialview01'>2rhs</scene>, resolution 2.200&Aring;
+
<StructureSection load='2rhs' size='340' side='right'caption='[[2rhs]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=GAX:'>GAX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
+
<table><tr><td colspan='2'>[[2rhs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_haemolyticus Staphylococcus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RHS FirstGlance]. <br>
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylalanine--tRNA_ligase Phenylalanine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.20 6.1.1.20] </span>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
|GENE= pheS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1283 Staphylococcus haemolyticus]), pheT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1283 Staphylococcus haemolyticus])
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAX:1-{3-[(4-PYRIDIN-2-YLPIPERAZIN-1-YL)SULFONYL]PHENYL}-3-(1,3-THIAZOL-2-YL)UREA'>GAX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
|DOMAIN=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rhs OCA], [https://pdbe.org/2rhs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rhs RCSB], [https://www.ebi.ac.uk/pdbsum/2rhs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rhs ProSAT]</span></td></tr>
-
|RELATEDENTRY=[[2rhq|2RHQ]]
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rhs OCA], [http://www.ebi.ac.uk/pdbsum/2rhs PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2rhs RCSB]</span>
+
== Function ==
-
}}
+
[https://www.uniprot.org/uniprot/SYFA_STAHJ SYFA_STAHJ]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rh/2rhs_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rhs ConSurf].
 +
<div style="clear:both"></div>
-
'''PheRS from Staphylococcus haemolyticus- rational protein engineering and inhibitor studies'''
+
==See Also==
-
 
+
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
2RHS is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Staphylococcus_haemolyticus Staphylococcus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RHS OCA].
+
[[Category: Large Structures]]
-
[[Category: Phenylalanine--tRNA ligase]]
+
-
[[Category: Protein complex]]
+
[[Category: Staphylococcus haemolyticus]]
[[Category: Staphylococcus haemolyticus]]
-
[[Category: Evdokimov, A G.]]
+
[[Category: Evdokimov AG]]
-
[[Category: Mekel, M.]]
+
[[Category: Mekel M]]
-
[[Category: aminoacyl-trna synthetase]]
+
-
[[Category: atp-binding]]
+
-
[[Category: cytoplasm]]
+
-
[[Category: heterotetramer]]
+
-
[[Category: ligase]]
+
-
[[Category: magnesium]]
+
-
[[Category: metal-binding]]
+
-
[[Category: nucleotide-binding]]
+
-
[[Category: phenylalanine]]
+
-
[[Category: protein biosynthesis]]
+
-
[[Category: rna-binding]]
+
-
[[Category: trna]]
+
-
[[Category: trna-binding]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:00:28 2008''
+

Current revision

PheRS from Staphylococcus haemolyticus- rational protein engineering and inhibitor studies

PDB ID 2rhs

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2rhs"
Personal tools