This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2rl1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:54, 13 March 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2rl1.jpg|left|200px]]
 
-
{{Structure
+
==Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine==
-
|PDB= 2rl1 |SIZE=350|CAPTION= <scene name='initialview01'>2rl1</scene>, resolution 2.200&Aring;
+
<StructureSection load='2rl1' size='340' side='right'caption='[[2rl1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+713'>AC1</scene> and <scene name='pdbsite=AC2:Ud1+Binding+Site+For+Residue+A+712'>AC2</scene>
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UD1:URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE'>UD1</scene>
+
<table><tr><td colspan='2'>[[2rl1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RL1 FirstGlance]. <br>
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_1-carboxyvinyltransferase UDP-N-acetylglucosamine 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.7 2.5.1.7] </span>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
|GENE= MurZ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 Haemophilus influenzae])
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UD1:URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE'>UD1</scene></td></tr>
-
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK09369 PRK09369], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01555 UdpNAET]</span>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rl1 OCA], [https://pdbe.org/2rl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rl1 RCSB], [https://www.ebi.ac.uk/pdbsum/2rl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rl1 ProSAT]</span></td></tr>
-
|RELATEDENTRY=[[2rl2|2RL2]]
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rl1 OCA], [http://www.ebi.ac.uk/pdbsum/2rl1 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2rl1 RCSB]</span>
+
== Function ==
-
}}
+
[https://www.uniprot.org/uniprot/MURA_HAEIN MURA_HAEIN] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rl/2rl1_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rl1 ConSurf].
 +
<div style="clear:both"></div>
-
'''Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine'''
+
==See Also==
-
 
+
*[[Enoylpyruvate transferase 3D structures|Enoylpyruvate transferase 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
2RL1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RL1 OCA].
+
-
 
+
-
==Reference==
+
-
Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine and fosfomycin., Yoon HJ, Lee SJ, Mikami B, Park HJ, Yoo J, Suh SW, Proteins. 2008 Feb 4;71(2):1032-1037. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18247346 18247346]
+
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: UDP-N-acetylglucosamine 1-carboxyvinyltransferase]]
+
[[Category: Suh SW]]
-
[[Category: Suh, S W.]]
+
[[Category: Yoon HJ]]
-
[[Category: Yoon, H J.]]
+
-
[[Category: cell cycle]]
+
-
[[Category: cell division]]
+
-
[[Category: cell shape]]
+
-
[[Category: cell wall biogenesis/degradation]]
+
-
[[Category: cytoplasm]]
+
-
[[Category: mura]]
+
-
[[Category: murz]]
+
-
[[Category: peptidoglycan synthesis]]
+
-
[[Category: transferase]]
+
-
[[Category: udp-n-acetylglucosamine]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:01:37 2008''
+

Current revision

Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine

PDB ID 2rl1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools