6hwl
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Glucosamine kinase in complex with glucosamine, ADP and inorganic phosphate== | |
| - | + | <StructureSection load='6hwl' size='340' side='right'caption='[[6hwl]], [[Resolution|resolution]] 2.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6hwl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptacidiphilus_jiangxiensis Streptacidiphilus jiangxiensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6HWL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.148Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GCS:D-GLUCOSAMINE'>GCS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6hwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hwl OCA], [https://pdbe.org/6hwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6hwl RCSB], [https://www.ebi.ac.uk/pdbsum/6hwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6hwl ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GLCNK_STRJI GLCNK_STRJI] Catalyzes the ATP-dependent phosphorylation of D-glucosamine (GlcN) to D-glucosamine 6-phosphate. May be involved in the phosphorylation of acquired extracellular GlcN derived from the hydrolysis of chitosan, i.e., in the incorporation of exogenous GlcN into the bacterial GlcNAc metabolism. To a lesser extent, is also active on glucose, but is unable to phosphorylate maltose, 18 other sugars and several aminoglycoside antibiotics.<ref>PMID:31088917</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Streptacidiphilus jiangxiensis]] | ||
| + | [[Category: Manso JA]] | ||
| + | [[Category: Pereira PJB]] | ||
Current revision
Glucosamine kinase in complex with glucosamine, ADP and inorganic phosphate
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