5m0r

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==Cryo-EM reconstruction of the maedi-visna virus (MVV) strand transfer complex==
==Cryo-EM reconstruction of the maedi-visna virus (MVV) strand transfer complex==
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<StructureSection load='5m0r' size='340' side='right' caption='[[5m0r]], [[Resolution|resolution]] 8.20&Aring;' scene=''>
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<SX load='5m0r' size='340' side='right' viewer='molstar' caption='[[5m0r]], [[Resolution|resolution]] 8.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5m0r]] is a 22 chain structure with sequence from [http://en.wikipedia.org/wiki/Mvv Mvv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M0R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M0R FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5m0r]] is a 22 chain structure with sequence from [https://en.wikipedia.org/wiki/Visna_lentivirus_(strain_1514) Visna lentivirus (strain 1514)], [https://en.wikipedia.org/wiki/Visna/maedi_virus_EV1_KV1772 Visna/maedi virus EV1 KV1772] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M0R FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36374 MVV])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m0r OCA], [http://pdbe.org/5m0r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m0r RCSB], [http://www.ebi.ac.uk/pdbsum/5m0r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m0r ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m0r OCA], [https://pdbe.org/5m0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m0r RCSB], [https://www.ebi.ac.uk/pdbsum/5m0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m0r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/POL_VILVK POL_VILVK]] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.
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[https://www.uniprot.org/uniprot/POL_VILVK POL_VILVK] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Retroviral Integrase|Retroviral Integrase]]
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*[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Mvv]]
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[[Category: Large Structures]]
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[[Category: Ballandras-Colas, A]]
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[[Category: Synthetic construct]]
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[[Category: Cherepanov, P]]
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[[Category: Visna/maedi virus EV1 KV1772]]
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[[Category: Costa, A]]
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[[Category: Ballandras-Colas A]]
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[[Category: Kotecha, A]]
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[[Category: Cherepanov P]]
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[[Category: Locke, J]]
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[[Category: Costa A]]
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[[Category: Maskell, D]]
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[[Category: Kotecha A]]
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[[Category: Pye, V E]]
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[[Category: Locke J]]
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[[Category: Dna-binding]]
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[[Category: Maskell D]]
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[[Category: Hydrolase]]
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[[Category: Pye VE]]
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[[Category: Integrase]]
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[[Category: Lentivirus]]
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[[Category: Retrovirus]]
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[[Category: Rnaseh fold]]
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[[Category: Zn-binding]]
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Current revision

Cryo-EM reconstruction of the maedi-visna virus (MVV) strand transfer complex

5m0r, resolution 8.20Å

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