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5m0r
From Proteopedia
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==Cryo-EM reconstruction of the maedi-visna virus (MVV) strand transfer complex== | ==Cryo-EM reconstruction of the maedi-visna virus (MVV) strand transfer complex== | ||
| - | < | + | <SX load='5m0r' size='340' side='right' viewer='molstar' caption='[[5m0r]], [[Resolution|resolution]] 8.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5m0r]] is a 22 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5m0r]] is a 22 chain structure with sequence from [https://en.wikipedia.org/wiki/Visna_lentivirus_(strain_1514) Visna lentivirus (strain 1514)], [https://en.wikipedia.org/wiki/Visna/maedi_virus_EV1_KV1772 Visna/maedi virus EV1 KV1772] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M0R FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.2Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m0r OCA], [https://pdbe.org/5m0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m0r RCSB], [https://www.ebi.ac.uk/pdbsum/5m0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m0r ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/POL_VILVK POL_VILVK] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[Retroviral | + | *[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
| - | </ | + | </SX> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Ballandras-Colas | + | [[Category: Synthetic construct]] |
| - | [[Category: Cherepanov | + | [[Category: Visna/maedi virus EV1 KV1772]] |
| - | [[Category: Costa | + | [[Category: Ballandras-Colas A]] |
| - | [[Category: Kotecha | + | [[Category: Cherepanov P]] |
| - | [[Category: Locke | + | [[Category: Costa A]] |
| - | [[Category: Maskell | + | [[Category: Kotecha A]] |
| - | [[Category: Pye | + | [[Category: Locke J]] |
| - | + | [[Category: Maskell D]] | |
| - | + | [[Category: Pye VE]] | |
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Current revision
Cryo-EM reconstruction of the maedi-visna virus (MVV) strand transfer complex
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