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5qhf

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'''Unreleased structure'''
 
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The entry 5qhf is ON HOLD
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==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with NUOOA000301a==
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<StructureSection load='5qhf' size='340' side='right'caption='[[5qhf]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
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Authors: Krojer, T., Talon, R., Fairhead, M., Diaz Saez, L., Bradley, A.R., Aimon, A., Collins, P., Brandao-Neto, J., Douangamath, A., Ruda, G.F., Szommer, T., Srikannathasan, V., Elkins, J., Spencer, J., London, N., Nelson, A., Brennan, P.E., Huber, K., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5qhf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QHF FirstGlance]. <br>
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Description: PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) --Crystal Structure of NUDT7 in complex with NUOOA000301a
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=H1G:2-(4-methoxyphenyl)-N-{5-[2-oxo-2-(3-oxopiperazin-1-yl)ethoxy]pyridin-3-yl}acetamide'>H1G</scene>, <scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>
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[[Category: Spencer, J]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhf OCA], [https://pdbe.org/5qhf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qhf RCSB], [https://www.ebi.ac.uk/pdbsum/5qhf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhf ProSAT]</span></td></tr>
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[[Category: Aimon, A]]
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</table>
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[[Category: Elkins, J]]
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== Function ==
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[[Category: Collins, P]]
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[https://www.uniprot.org/uniprot/NUDT7_HUMAN NUDT7_HUMAN] Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products. CoA into 3',5'-ADP and 4'-phosphopantetheine. Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA (By similarity).
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[[Category: Huber, K]]
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__TOC__
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[[Category: Ruda, G.F]]
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</StructureSection>
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[[Category: Arrowsmith, C.H]]
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[[Category: Homo sapiens]]
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[[Category: Brandao-Neto, J]]
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[[Category: Large Structures]]
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[[Category: Diaz Saez, L]]
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[[Category: Aimon A]]
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[[Category: Fairhead, M]]
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[[Category: Arrowsmith CH]]
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[[Category: Von Delft, F]]
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[[Category: Bountra C]]
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[[Category: Bradley, A.R]]
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[[Category: Bradley AR]]
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[[Category: Talon, R]]
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[[Category: Brandao-Neto J]]
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[[Category: Brennan, P.E]]
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[[Category: Brennan PE]]
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[[Category: Edwards, A]]
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[[Category: Collins P]]
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[[Category: Douangamath, A]]
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[[Category: Diaz Saez L]]
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[[Category: Szommer, T]]
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[[Category: Douangamath A]]
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[[Category: Krojer, T]]
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[[Category: Edwards A]]
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[[Category: Srikannathasan, V]]
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[[Category: Elkins J]]
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[[Category: Bountra, C]]
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[[Category: Fairhead M]]
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[[Category: Nelson, A]]
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[[Category: Huber K]]
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[[Category: London, N]]
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[[Category: Krojer T]]
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[[Category: London N]]
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[[Category: Nelson A]]
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[[Category: Ruda GF]]
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[[Category: Spencer J]]
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[[Category: Srikannathasan V]]
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[[Category: Szommer T]]
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[[Category: Talon R]]
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[[Category: Von Delft F]]

Current revision

PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with NUOOA000301a

PDB ID 5qhf

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