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6ioz
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6ioz is ON HOLD Authors: Kim, H., Kim, D., Hong, J., Lee, K., Seo, J., Oh, B.H. Description: Structural insights of idursulfase beta [[Category: Un...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structural insights of idursulfase beta== | |
| + | <StructureSection load='6ioz' size='340' side='right'caption='[[6ioz]], [[Resolution|resolution]] 3.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6ioz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IOZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IOZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALS:(3S)-3-(SULFOOXY)-L-SERINE'>ALS</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ioz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ioz OCA], [https://pdbe.org/6ioz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ioz RCSB], [https://www.ebi.ac.uk/pdbsum/6ioz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ioz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/IDS_HUMAN IDS_HUMAN] Mucopolysaccharidosis type 2, attenuated form;Mucopolysaccharidosis type 2, severe form. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IDS_HUMAN IDS_HUMAN] Required for the lysosomal degradation of heparan sulfate and dermatan sulfate. | ||
| - | + | ==See Also== | |
| - | + | *[[Sulfatase 3D structures|Sulfatase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Hong | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Hong J]] |
| - | [[Category: | + | [[Category: Kim D]] |
| - | [[Category: Oh | + | [[Category: Kim H]] |
| - | [[Category: | + | [[Category: Lee K]] |
| + | [[Category: Oh BH]] | ||
| + | [[Category: Seo J]] | ||
Current revision
Structural insights of idursulfase beta
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Categories: Homo sapiens | Large Structures | Hong J | Kim D | Kim H | Lee K | Oh BH | Seo J
