3cne

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==Crystal structure of the putative protease I from Bacteroides thetaiotaomicron==
==Crystal structure of the putative protease I from Bacteroides thetaiotaomicron==
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<StructureSection load='3cne' size='340' side='right' caption='[[3cne]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
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<StructureSection load='3cne' size='340' side='right'caption='[[3cne]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3cne]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bactn Bactn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CNE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3cne]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron_VPI-5482 Bacteroides thetaiotaomicron VPI-5482]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CNE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CNE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GI:29338570, BT_1263 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=226186 BACTN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cne OCA], [https://pdbe.org/3cne PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cne RCSB], [https://www.ebi.ac.uk/pdbsum/3cne PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cne ProSAT], [https://www.topsan.org/Proteins/MCSG/3cne TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cne OCA], [http://pdbe.org/3cne PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cne RCSB], [http://www.ebi.ac.uk/pdbsum/3cne PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3cne ProSAT], [http://www.topsan.org/Proteins/MCSG/3cne TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PPBAT_BACTN PPBAT_BACTN] Binds flavin derivatives, such as lumichrome, riboflavin, FMN, and FAD (PubMed:22718753, PubMed:25263158). May act as a flavin storage protein (PubMed:22718753, PubMed:25263158). Appears to lack proteolytic or chaperone activities (PubMed:25263158).<ref>PMID:22718753</ref> <ref>PMID:25263158</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cn/3cne_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cn/3cne_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cne ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cne ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bactn]]
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[[Category: Bacteroides thetaiotaomicron VPI-5482]]
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[[Category: Abdullah, J]]
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[[Category: Large Structures]]
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[[Category: Joachimiak, A]]
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[[Category: Abdullah J]]
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[[Category: Structural genomic]]
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[[Category: Joachimiak A]]
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[[Category: Volkart, L]]
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[[Category: Volkart L]]
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[[Category: Zhang, R]]
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[[Category: Zhang R]]
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[[Category: Hydrolase]]
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[[Category: Mcsg]]
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[[Category: Protease i]]
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[[Category: PSI, Protein structure initiative]]
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Current revision

Crystal structure of the putative protease I from Bacteroides thetaiotaomicron

PDB ID 3cne

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