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RNA-guided pseudouridine synthase
From Proteopedia
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| - | {{Stub} | + | {{Stub}} |
| - | <StructureSection load='3hay' size='400' side='right' caption= | + | <StructureSection load='3hay' size='400' side='right' caption='Pyrococcus furiosus RNA-guided Pseudouridine synthase (grey) in complex with small nucleolarRNP Gar-like protein (green), ribosome biogenesis protein Nop10 (pink), 50S ribosomal protein L7AE (yellow), RNA, pseudouridine derivative and Zn+2 ion (grey) (PDB code [[3hay]])' scene='' pspeed='8'> |
== Function == | == Function == | ||
H/ACA ribonucleoproteins that use RNAs to guide [[pseudouridine|pseudouridine]] formation. | H/ACA ribonucleoproteins that use RNAs to guide [[pseudouridine|pseudouridine]] formation. | ||
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==Structures of RNA-guided pseudoridine synthase== | ==Structures of RNA-guided pseudoridine synthase== | ||
| - | Eukaryotic | + | * Eukaryotic |
| - | * [[Cbf5-Nop10-Gar1 | + | ** [[3u28]] Cbf5-Nop10-Gar1 complex (''Saccharomyces cerevisiae'') |
| - | Archaeal | + | * Archaeal |
| - | ** [[3hay]] - the full complex with substrate RNA ( ''Pyrococcus furiosus'') | + | ** [[3hay]] - the full complex with substrate RNA (''Pyrococcus furiosus'') |
** [[3hjw]] - the Cbf5-L7Ae-Nop10-guide RNA-substrate RNA complex (''Pyrococcus furiosus'') | ** [[3hjw]] - the Cbf5-L7Ae-Nop10-guide RNA-substrate RNA complex (''Pyrococcus furiosus'') | ||
** [[2hvy]] - Cbf5-Gar1-L7Ae-Nop10-guide RNA complex (''Pyrococcus furiosus'') | ** [[2hvy]] - Cbf5-Gar1-L7Ae-Nop10-guide RNA complex (''Pyrococcus furiosus'') | ||
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