This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6mzc

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "6mzc" [edit=sysop:move=sysop])
Current revision (14:45, 13 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 6mzc is ON HOLD
+
==Human TFIID BC core==
 +
<SX load='6mzc' size='340' side='right' viewer='molstar' caption='[[6mzc]], [[Resolution|resolution]] 4.50&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[6mzc]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MZC FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.5&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mzc OCA], [https://pdbe.org/6mzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mzc RCSB], [https://www.ebi.ac.uk/pdbsum/6mzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mzc ProSAT]</span></td></tr>
 +
</table>
 +
== Disease ==
 +
[https://www.uniprot.org/uniprot/TAF2_HUMAN TAF2_HUMAN] Microcephaly-thin corpus callosum-intellectual disability syndrome. The disease is caused by mutations affecting the gene represented in this entry.
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TAF2_HUMAN TAF2_HUMAN] Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. It requires core promoter-specific cofactors for productive transcription stimulation. TAF2 stabilizes TFIID binding to core promoter.<ref>PMID:9418870</ref> <ref>PMID:9774672</ref>
-
Authors:
+
==See Also==
-
 
+
*[[Transcription initiation factors 3D structures|Transcription initiation factors 3D structures]]
-
Description:
+
== References ==
-
[[Category: Unreleased Structures]]
+
<references/>
 +
__TOC__
 +
</SX>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Fang J]]
 +
[[Category: Greber BJ]]
 +
[[Category: Grunberg S]]
 +
[[Category: Hahn S]]
 +
[[Category: Liu Y]]
 +
[[Category: Louder RK]]
 +
[[Category: Luo J]]
 +
[[Category: Nogales E]]
 +
[[Category: Patel AB]]
 +
[[Category: Ranish J]]

Current revision

Human TFIID BC core

6mzc, resolution 4.50Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6mzc"
Personal tools