6mgp

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==Structure of human 4-1BB / 4-1BBL complex==
==Structure of human 4-1BB / 4-1BBL complex==
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<StructureSection load='6mgp' size='340' side='right' caption='[[6mgp]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
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<StructureSection load='6mgp' size='340' side='right'caption='[[6mgp]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6mgp]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MGP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MGP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6mgp]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MGP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.13&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6mge|6mge]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mgp OCA], [http://pdbe.org/6mgp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mgp RCSB], [http://www.ebi.ac.uk/pdbsum/6mgp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mgp ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mgp OCA], [https://pdbe.org/6mgp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mgp RCSB], [https://www.ebi.ac.uk/pdbsum/6mgp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mgp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TNFL9_HUMAN TNFL9_HUMAN]] Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. [[http://www.uniprot.org/uniprot/TNR9_HUMAN TNR9_HUMAN]] Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
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[https://www.uniprot.org/uniprot/TNFL9_HUMAN TNFL9_HUMAN] Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
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==See Also==
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*[[Tumor necrosis factor ligand superfamily 3D structures|Tumor necrosis factor ligand superfamily 3D structures]]
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*[[Tumor necrosis factor receptor 3D structures|Tumor necrosis factor receptor 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chin, S M]]
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[[Category: Homo sapiens]]
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[[Category: Kimberlin, C R]]
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[[Category: Large Structures]]
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[[Category: Roe-Zurz, Z]]
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[[Category: Chin SM]]
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[[Category: Xu, A]]
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[[Category: Kimberlin CR]]
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[[Category: Yang, Y]]
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[[Category: Roe-Zurz Z]]
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[[Category: 4-1bb]]
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[[Category: Xu A]]
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[[Category: 4-1bbl]]
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[[Category: Yang Y]]
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[[Category: Cd137]]
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[[Category: Cd137l]]
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[[Category: Complex]]
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[[Category: Immune system]]
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[[Category: Signaling]]
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[[Category: Tnfrsf]]
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[[Category: Tnfsf]]
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Current revision

Structure of human 4-1BB / 4-1BBL complex

PDB ID 6mgp

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