6i5u
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM informed directed evolution of Nitrilase 4 leads to a change in quaternary structure.== | |
| - | + | <SX load='6i5u' size='340' side='right' viewer='molstar' caption='[[6i5u]], [[Resolution|resolution]] 3.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6i5u]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I5U OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6I5U FirstGlance]. <br> | |
| - | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NIT4, At5g22300, MWD9.8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6i5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i5u OCA], [http://pdbe.org/6i5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i5u RCSB], [http://www.ebi.ac.uk/pdbsum/6i5u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i5u ProSAT]</span></td></tr> |
| - | [[Category: Mulelu, A | + | </table> |
| - | [[Category: Woodward, J | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/NRL4_ARATH NRL4_ARATH]] Highly specific for beta-cyano-L-alanine (Ala(CN)). Low activity with 3-phenylpropionitrile (PPN) or allylcyanide and no activity with indole-3-acetonitrile. Not associated with auxin production but may be involved in cyanide detoxification.<ref>PMID:11060302</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Arath]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mulelu, A E]] | ||
| + | [[Category: Woodward, J D]] | ||
| + | [[Category: Beta-cyano-l-alanine hydrolase]] | ||
| + | [[Category: Cyanide detoxification]] | ||
| + | [[Category: Helical filament]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Nitrilase]] | ||
Current revision
Cryo-EM informed directed evolution of Nitrilase 4 leads to a change in quaternary structure.
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