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2yvv

From Proteopedia

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[[Image:2yvv.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of hyluranidase complexed with lactose at 2.6 A resolution reveals three specific sugar recognition sites==
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|PDB= 2yvv |SIZE=350|CAPTION= <scene name='initialview01'>2yvv</scene>, resolution 2.60&Aring;
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<StructureSection load='2yvv' size='340' side='right'caption='[[2yvv]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=LBT:LACTOSE'>LBT</scene>
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<table><tr><td colspan='2'>[[2yvv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YVV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YVV FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Hyaluronate_lyase Hyaluronate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.2.1 4.2.2.1] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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|GENE= HYL P2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1314 Streptococcus pyogenes])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900008:alpha-lactose'>PRD_900008</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yvv OCA], [https://pdbe.org/2yvv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yvv RCSB], [https://www.ebi.ac.uk/pdbsum/2yvv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yvv ProSAT]</span></td></tr>
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|RELATEDENTRY=[[2dp5|2DP5]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yvv OCA], [http://www.ebi.ac.uk/pdbsum/2yvv PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2yvv RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/Q9A0M7_STRP1 Q9A0M7_STRP1]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yv/2yvv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yvv ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of hyluranidase complexed with lactose at 2.6 A resolution reveals three specific sugar recognition sites'''
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==See Also==
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*[[Hyaluronidase 3D structures|Hyaluronidase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2YVV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YVV OCA].
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[[Category: Large Structures]]
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[[Category: Hyaluronate lyase]]
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[[Category: Single protein]]
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[[Category: Streptococcus pyogenes]]
[[Category: Streptococcus pyogenes]]
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[[Category: Betzel, C.]]
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[[Category: Betzel C]]
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[[Category: Bhakuni, V.]]
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[[Category: Bhakuni V]]
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[[Category: Kaur, P.]]
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[[Category: Kaur P]]
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[[Category: Kumar, R Prem.]]
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[[Category: Mishra P]]
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[[Category: Mishra, P.]]
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[[Category: Perbandt M]]
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[[Category: Perbandt, M.]]
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[[Category: Prem Kumar R]]
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[[Category: Sharma, S.]]
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[[Category: Sharma S]]
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[[Category: Singh, N.]]
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[[Category: Singh N]]
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[[Category: Singh, T P.]]
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[[Category: Singh TP]]
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[[Category: complex]]
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[[Category: hyaluronan lyase]]
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[[Category: hyaluronidase]]
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[[Category: lactose]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:15:49 2008''
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Current revision

Crystal structure of hyluranidase complexed with lactose at 2.6 A resolution reveals three specific sugar recognition sites

PDB ID 2yvv

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