6isn
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Phosphoglycerate mutase 1 complexed with a small molecule inhibitor== | |
| + | <StructureSection load='6isn' size='340' side='right'caption='[[6isn]], [[Resolution|resolution]] 1.98Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6isn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ISN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ISN FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.98Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AW6:~{N}-[3,4-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen-2-yl]-4-chloranyl-benzenesulfonamide'>AW6</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NEP:N1-PHOSPHONOHISTIDINE'>NEP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6isn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6isn OCA], [https://pdbe.org/6isn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6isn RCSB], [https://www.ebi.ac.uk/pdbsum/6isn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6isn ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PGAM1_HUMAN PGAM1_HUMAN] Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. | ||
| - | + | ==See Also== | |
| - | + | *[[Phosphoglycerate mutase 3D structures|Phosphoglycerate mutase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Huang | + | [[Category: Homo sapiens]] |
| - | [[Category: Jiang | + | [[Category: Large Structures]] |
| - | [[Category: Zhou | + | [[Category: Huang K]] |
| + | [[Category: Jiang LL]] | ||
| + | [[Category: Zhou L]] | ||
Current revision
Phosphoglycerate mutase 1 complexed with a small molecule inhibitor
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