6n1z
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6n1z is ON HOLD Authors: Tomchick, D.R., Chook, Y.M., Padavannil, A. Description: Importin cargo complex Category: Unreleased Structures [[Cate...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Importin-9 bound to H2A-H2B== | |
| + | <StructureSection load='6n1z' size='340' side='right'caption='[[6n1z]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6n1z]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6N1Z FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6n1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n1z OCA], [https://pdbe.org/6n1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6n1z RCSB], [https://www.ebi.ac.uk/pdbsum/6n1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6n1z ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/H2A1_XENLA H2A1_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
| - | + | ==See Also== | |
| - | + | *[[Histone 3D structures|Histone 3D structures]] | |
| - | + | *[[Importin 3D structures|Importin 3D structures]] | |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Chook | + | [[Category: Large Structures]] |
| + | [[Category: Xenopus laevis]] | ||
| + | [[Category: Chook YM]] | ||
| + | [[Category: Padavannil A]] | ||
| + | [[Category: Tomchick DR]] | ||
Current revision
Importin-9 bound to H2A-H2B
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