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3edc

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==Crystal Structure of a 1.6-hexanediol Bound Tetrameric Form of Escherichia coli Lac-repressor Refined to 2.1 Resolution==
==Crystal Structure of a 1.6-hexanediol Bound Tetrameric Form of Escherichia coli Lac-repressor Refined to 2.1 Resolution==
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<StructureSection load='3edc' size='340' side='right' caption='[[3edc]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='3edc' size='340' side='right'caption='[[3edc]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3edc]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EDC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EDC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3edc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EDC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EDC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3edc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3edc OCA], [http://pdbe.org/3edc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3edc RCSB], [http://www.ebi.ac.uk/pdbsum/3edc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3edc ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3edc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3edc OCA], [https://pdbe.org/3edc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3edc RCSB], [https://www.ebi.ac.uk/pdbsum/3edc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3edc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LACI_ECOLI LACI_ECOLI]] Repressor of the lactose operon. Binds allolactose as an inducer.
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[https://www.uniprot.org/uniprot/LACI_ECOLI LACI_ECOLI] Repressor of the lactose operon. Binds allolactose as an inducer.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Stenberg, K A.E]]
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[[Category: Large Structures]]
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[[Category: Allosteric]]
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[[Category: Stenberg KAE]]
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[[Category: Dna-binding]]
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[[Category: Lac-repressor]]
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[[Category: Repressor]]
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[[Category: Tetramer]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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Current revision

Crystal Structure of a 1.6-hexanediol Bound Tetrameric Form of Escherichia coli Lac-repressor Refined to 2.1 Resolution

PDB ID 3edc

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