2zbt

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[[Image:2zbt.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of pyridoxine biosynthesis protein from Thermus thermophilus HB8==
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|PDB= 2zbt |SIZE=350|CAPTION= <scene name='initialview01'>2zbt</scene>, resolution 1.65&Aring;
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<StructureSection load='2zbt' size='340' side='right'caption='[[2zbt]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
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<table><tr><td colspan='2'>[[2zbt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZBT FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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|GENE= pdxS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zbt OCA], [https://pdbe.org/2zbt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zbt RCSB], [https://www.ebi.ac.uk/pdbsum/2zbt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zbt ProSAT], [https://www.topsan.org/Proteins/RSGI/2zbt TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zbt OCA], [http://www.ebi.ac.uk/pdbsum/2zbt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2zbt RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/PDXS_THET8 PDXS_THET8] Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.[HAMAP-Rule:MF_01824]
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== Evolutionary Conservation ==
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'''Crystal structure of pyridoxine biosynthesis protein from Thermus thermophilus HB8'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zb/2zbt_consurf.spt"</scriptWhenChecked>
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2ZBT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZBT OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Single protein]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Thermus thermophilus]]
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</jmolCheckbox>
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[[Category: Ebihara, A.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zbt ConSurf].
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[[Category: Fujimoto, Y.]]
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<div style="clear:both"></div>
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[[Category: Kuramitsu, S.]]
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__TOC__
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[[Category: Manzoku, M.]]
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</StructureSection>
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Large Structures]]
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[[Category: Yokoyama, S.]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: lyase]]
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[[Category: Ebihara A]]
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[[Category: national project on protein structural and functional analyse]]
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[[Category: Fujimoto Y]]
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[[Category: nppsfa]]
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[[Category: Kuramitsu S]]
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[[Category: pyridoxine biosynthesis]]
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[[Category: Manzoku M]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: Yokoyama S]]
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[[Category: rsgi]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:20:13 2008''
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Current revision

Crystal structure of pyridoxine biosynthesis protein from Thermus thermophilus HB8

PDB ID 2zbt

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