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3fwh

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==Structure of haloalkane dehalogenase mutant Dha15 (I135F/C176Y) from Rhodococcus rhodochrous==
==Structure of haloalkane dehalogenase mutant Dha15 (I135F/C176Y) from Rhodococcus rhodochrous==
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<StructureSection load='3fwh' size='340' side='right' caption='[[3fwh]], [[Resolution|resolution]] 1.22&Aring;' scene=''>
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<StructureSection load='3fwh' size='340' side='right'caption='[[3fwh]], [[Resolution|resolution]] 1.22&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3fwh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhoso Rhoso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FWH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3fwh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FWH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.22&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fbw|3fbw]], [[3g9x|3g9x]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dhaA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1831 RHOSO])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwh OCA], [https://pdbe.org/3fwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fwh RCSB], [https://www.ebi.ac.uk/pdbsum/3fwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fwh ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Haloalkane_dehalogenase Haloalkane dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.5 3.8.1.5] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fwh OCA], [http://pdbe.org/3fwh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fwh RCSB], [http://www.ebi.ac.uk/pdbsum/3fwh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fwh ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DHAA_RHOSO DHAA_RHOSO]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Dehalogenase|Dehalogenase]]
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*[[Dehalogenase 3D structures|Dehalogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Haloalkane dehalogenase]]
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[[Category: Large Structures]]
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[[Category: Rhoso]]
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[[Category: Rhodococcus sp]]
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[[Category: Dohnalek, J]]
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[[Category: Dohnalek J]]
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[[Category: Gavira, J A]]
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[[Category: Gavira JA]]
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[[Category: Kuty, M]]
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[[Category: Kuta Smatanova I]]
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[[Category: Lapkouski, M]]
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[[Category: Kuty M]]
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[[Category: Smatanova, I Kuta]]
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[[Category: Lapkouski M]]
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[[Category: Stsiapanava, A]]
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[[Category: Stsiapanava A]]
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[[Category: Alpha/beta hydrolase core]]
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[[Category: C176y]]
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[[Category: Detoxification]]
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[[Category: Haloalkane]]
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[[Category: Helical cap domain]]
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[[Category: His272]]
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[[Category: Hydrolase]]
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[[Category: I135f]]
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[[Category: Mutant]]
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Current revision

Structure of haloalkane dehalogenase mutant Dha15 (I135F/C176Y) from Rhodococcus rhodochrous

PDB ID 3fwh

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