This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3hay

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:48, 1 November 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Crystal structure of a substrate-bound full H/ACA RNP from Pyrococcus furiosus==
==Crystal structure of a substrate-bound full H/ACA RNP from Pyrococcus furiosus==
-
<StructureSection load='3hay' size='340' side='right' caption='[[3hay]], [[Resolution|resolution]] 4.99&Aring;' scene=''>
+
<StructureSection load='3hay' size='340' side='right'caption='[[3hay]], [[Resolution|resolution]] 4.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3hay]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HAY FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3hay]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HAY FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.99&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=FHU:(5S,6R)-5-FLUORO-6-HYDROXY-PSEUDOURIDINE-5-MONOPHOSPHATE'>FHU</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FHU:(5S,6R)-5-FLUORO-6-HYDROXY-PSEUDOURIDINE-5-MONOPHOSPHATE'>FHU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hax|3hax]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hay FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hay OCA], [https://pdbe.org/3hay PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hay RCSB], [https://www.ebi.ac.uk/pdbsum/3hay PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hay ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">truB, PF1785 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587]), PF1791 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587]), PF1141 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587]), rpl7ae, PF1367 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hay FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hay OCA], [http://pdbe.org/3hay PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hay RCSB], [http://www.ebi.ac.uk/pdbsum/3hay PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hay ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/RL7A_PYRFU RL7A_PYRFU]] Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). [[http://www.uniprot.org/uniprot/TRUB_PYRFU TRUB_PYRFU]] Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs (By similarity). [[http://www.uniprot.org/uniprot/NOP10_PYRFU NOP10_PYRFU]] Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA (By similarity).
+
[https://www.uniprot.org/uniprot/TRUB_PYRFU TRUB_PYRFU] Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 35: Line 33:
*[[Guide-independent Pseudouridine synthase|Guide-independent Pseudouridine synthase]]
*[[Guide-independent Pseudouridine synthase|Guide-independent Pseudouridine synthase]]
*[[Kink-turn motif|Kink-turn motif]]
*[[Kink-turn motif|Kink-turn motif]]
-
*[[RNA-guided pseudouridine synthase|RNA-guided pseudouridine synthase]]
+
*[[Pseudouridine synthase 3D structures|Pseudouridine synthase 3D structures]]
*[[Ribosome biogenesis protein|Ribosome biogenesis protein]]
*[[Ribosome biogenesis protein|Ribosome biogenesis protein]]
 +
*[[Ribosome biogenesis protein 3D structures|Ribosome biogenesis protein 3D structures]]
*[[User:Wayne Decatur/kink-turn motif|User:Wayne Decatur/kink-turn motif]]
*[[User:Wayne Decatur/kink-turn motif|User:Wayne Decatur/kink-turn motif]]
== References ==
== References ==
Line 42: Line 41:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Atcc 43587]]
+
[[Category: Large Structures]]
-
[[Category: Ye, K]]
+
[[Category: Pyrococcus furiosus]]
-
[[Category: Guide rna]]
+
[[Category: Ye K]]
-
[[Category: H/aca]]
+
-
[[Category: Isomerase]]
+
-
[[Category: Isomerase-biosynthetic protein-rna complex]]
+
-
[[Category: Pseudouridine synthase]]
+
-
[[Category: Ribonucleoprotein]]
+
-
[[Category: Ribosomal protein]]
+
-
[[Category: Ribosome biogenesis]]
+
-
[[Category: Rna-binding]]
+
-
[[Category: Rna-protein complex]]
+
-
[[Category: Rrna processing]]
+
-
[[Category: Trna processing]]
+

Current revision

Crystal structure of a substrate-bound full H/ACA RNP from Pyrococcus furiosus

PDB ID 3hay

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3hay"
Personal tools