3b6u

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[[Image:3b6u.gif|left|200px]]
 
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{{Structure
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==Crystal structure of the motor domain of human kinesin family member 3B in complex with ADP==
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|PDB= 3b6u |SIZE=350|CAPTION= <scene name='initialview01'>3b6u</scene>, resolution 1.800&Aring;
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<StructureSection load='3b6u' size='340' side='right'caption='[[3b6u]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=ADP:ADENOSINE-5&#39;-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>
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<table><tr><td colspan='2'>[[3b6u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B6U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B6U FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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|GENE= KIF3B, KIAA0359 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b6u OCA], [https://pdbe.org/3b6u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b6u RCSB], [https://www.ebi.ac.uk/pdbsum/3b6u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b6u ProSAT]</span></td></tr>
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|RELATEDENTRY=[[3b6v|3B6V]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b6u OCA], [http://www.ebi.ac.uk/pdbsum/3b6u PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3b6u RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/KIF3B_HUMAN KIF3B_HUMAN] Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/3b6u_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b6u ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of the motor domain of human kinesin family member 3B in complex with ADP'''
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==See Also==
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*[[Kinesin 3D Structures|Kinesin 3D Structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3B6U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B6U OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith CH]]
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[[Category: Bochkarev, A.]]
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[[Category: Bochkarev A]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards AM]]
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[[Category: Landry, R.]]
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[[Category: Landry R]]
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[[Category: Park, H.]]
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[[Category: Park H]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Shen Y]]
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[[Category: Shen, Y.]]
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[[Category: Sundstrom M]]
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[[Category: Sundstrom, M.]]
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[[Category: Tempel W]]
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[[Category: Tempel, W.]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J.]]
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[[Category: Zhu H]]
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[[Category: Zhu, H.]]
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[[Category: adp]]
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[[Category: atp-binding]]
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[[Category: coiled coil]]
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[[Category: kinesin]]
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[[Category: microtubule]]
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[[Category: motor domain]]
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[[Category: motor protein]]
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[[Category: nucleotide-binding]]
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[[Category: sgc]]
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[[Category: structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:23:35 2008''
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Current revision

Crystal structure of the motor domain of human kinesin family member 3B in complex with ADP

PDB ID 3b6u

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