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3b9c

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[[Image:3b9c.jpg|left|200px]]
 
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{{Structure
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==Crystal Structure of Human GRP CRD==
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|PDB= 3b9c |SIZE=350|CAPTION= <scene name='initialview01'>3b9c</scene>, resolution 1.90&Aring;
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<StructureSection load='3b9c' size='340' side='right'caption='[[3b9c]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+137'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+D+137'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+D+138'>AC3</scene>, <scene name='pdbsite=AC4:So4+Binding+Site+For+Residue+C+137'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+B+137'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+A+138'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Residue+B+138'>AC7</scene>, <scene name='pdbsite=AC8:Bme+Binding+Site+For+Residue+D+139'>AC8</scene>, <scene name='pdbsite=AC9:Bme+Binding+Site+For+Residue+A+139'>AC9</scene>, <scene name='pdbsite=BC1:Bme+Binding+Site+For+Residue+B+139'>BC1</scene>, <scene name='pdbsite=BC2:Bme+Binding+Site+For+Residue+D+140'>BC2</scene>, <scene name='pdbsite=BC3:Bme+Binding+Site+For+Residue+C+138'>BC3</scene> and <scene name='pdbsite=BC4:Bme+Binding+Site+For+Residue+C+139'>BC4</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[3b9c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B9C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B9C FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b9c OCA], [https://pdbe.org/3b9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b9c RCSB], [https://www.ebi.ac.uk/pdbsum/3b9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b9c ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b9c OCA], [http://www.ebi.ac.uk/pdbsum/3b9c PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3b9c RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/LEGL_HUMAN LEGL_HUMAN] Does not bind lactose, and may not bind carbohydrates.<ref>PMID:18320588</ref> <ref>PMID:18433051</ref>
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== Evolutionary Conservation ==
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'''Crystal Structure of Human GRP CRD'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b9/3b9c_consurf.spt"</scriptWhenChecked>
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3B9C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B9C OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==Reference==
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</jmolCheckbox>
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Crystal structure of the C-terminal conserved domain of human GRP, a galectin-related protein, reveals a function mode different from those of galectins., Zhou D, Ge H, Sun J, Gao Y, Teng M, Niu L, Proteins. 2008 Mar 4;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18320588 18320588]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b9c ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Ge, H H.]]
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[[Category: Ge HH]]
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[[Category: Niu, L W.]]
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[[Category: Niu LW]]
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[[Category: Teng, M K.]]
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[[Category: Teng MK]]
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[[Category: Zhou, D.]]
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[[Category: Zhou D]]
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[[Category: beta sandwich]]
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[[Category: unknown function]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:24:24 2008''
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Current revision

Crystal Structure of Human GRP CRD

PDB ID 3b9c

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