3hup

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==High-resolution structure of the extracellular domain of human CD69==
==High-resolution structure of the extracellular domain of human CD69==
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<StructureSection load='3hup' size='340' side='right' caption='[[3hup]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
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<StructureSection load='3hup' size='340' side='right'caption='[[3hup]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hup]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HUP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hup]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HUP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.371&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3cck|3cck]], [[1fm5|1fm5]], [[1e8i|1e8i]], [[1e87|1e87]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD69 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hup OCA], [https://pdbe.org/3hup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hup RCSB], [https://www.ebi.ac.uk/pdbsum/3hup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hup ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hup OCA], [http://pdbe.org/3hup PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hup RCSB], [http://www.ebi.ac.uk/pdbsum/3hup PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hup ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CD69_HUMAN CD69_HUMAN]] Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
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[https://www.uniprot.org/uniprot/CD69_HUMAN CD69_HUMAN] Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hu/3hup_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hu/3hup_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Bezouska, K]]
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[[Category: Large Structures]]
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[[Category: Dohnalek, J]]
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[[Category: Bezouska K]]
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[[Category: Duskova, J]]
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[[Category: Dohnalek J]]
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[[Category: Hasek, J]]
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[[Category: Duskova J]]
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[[Category: Kolenko, P]]
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[[Category: Hasek J]]
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[[Category: Skalova, T]]
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[[Category: Kolenko P]]
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[[Category: Vanek, O]]
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[[Category: Skalova T]]
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[[Category: C-type lectin-like domain]]
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[[Category: Vanek O]]
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[[Category: Disulfide bond]]
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[[Category: Glycoprotein]]
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[[Category: Immune system]]
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[[Category: Lectin]]
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[[Category: Membrane]]
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[[Category: Phosphoprotein]]
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[[Category: Signal-anchor]]
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[[Category: Transmembrane]]
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Current revision

High-resolution structure of the extracellular domain of human CD69

PDB ID 3hup

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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