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5qjr
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==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT5 in complex with Z220816104== | ==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT5 in complex with Z220816104== | ||
| - | <StructureSection load='5qjr' size='340' side='right' caption='[[5qjr]], [[Resolution|resolution]] 1.62Å' scene=''> | + | <StructureSection load='5qjr' size='340' side='right'caption='[[5qjr]], [[Resolution|resolution]] 1.62Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5qjr]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QJR OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5qjr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QJR FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K1V:(3R)-1-acetylpiperidine-3-carboxamide'>K1V</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.62Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K1V:(3R)-1-acetylpiperidine-3-carboxamide'>K1V</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qjr OCA], [https://pdbe.org/5qjr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qjr RCSB], [https://www.ebi.ac.uk/pdbsum/5qjr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qjr ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/NUDT5_HUMAN NUDT5_HUMAN] Hydrolyzes with similar activities ADP-ribose ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity.<ref>PMID:17052728</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Arrowsmith | + | [[Category: Homo sapiens]] |
| - | [[Category: Bountra | + | [[Category: Large Structures]] |
| - | [[Category: Burgess-Brown | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Collins | + | [[Category: Bountra C]] |
| - | + | [[Category: Burgess-Brown N]] | |
| - | [[Category: Dubianok | + | [[Category: Collins P]] |
| - | [[Category: Edwards | + | [[Category: Dubianok Y]] |
| - | [[Category: Huber | + | [[Category: Edwards A]] |
| - | [[Category: Krojer | + | [[Category: Huber K]] |
| - | [[Category: Strain-Damerell | + | [[Category: Krojer T]] |
| - | [[Category: Wright | + | [[Category: Strain-Damerell C]] |
| - | [[Category: | + | [[Category: Wright N]] |
| - | + | [[Category: Von Delft F]] | |
| - | + | ||
| - | + | ||
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Current revision
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT5 in complex with Z220816104
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