3brq

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[[Image:3brq.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of the Escherichia coli transcriptional repressor ascG==
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|PDB= 3brq |SIZE=350|CAPTION= <scene name='initialview01'>3brq</scene>, resolution 2.00&Aring;
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<StructureSection load='3brq' size='340' side='right'caption='[[3brq]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[3brq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BRQ FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|GENE= ascG, b2714, JW5434 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 Escherichia coli K12])
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ascG, b2714, JW5434 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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|RELATEDENTRY=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3brq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brq OCA], [https://pdbe.org/3brq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3brq RCSB], [https://www.ebi.ac.uk/pdbsum/3brq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3brq ProSAT], [https://www.topsan.org/Proteins/MCSG/3brq TOPSAN]</span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3brq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brq OCA], [http://www.ebi.ac.uk/pdbsum/3brq PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3brq RCSB]</span>
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</table>
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}}
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== Function ==
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[[https://www.uniprot.org/uniprot/ASCG_ECOLI ASCG_ECOLI]] Repressor of the asc operon. The cryptic operon is activated by the insertion of IS186 into the ascG gene.
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'''Crystal structure of the Escherichia coli transcriptional repressor ascG'''
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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==About this Structure==
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<jmolCheckbox>
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3BRQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k12 Escherichia coli k12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRQ OCA].
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/3brq_consurf.spt"</scriptWhenChecked>
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[[Category: Escherichia coli k12]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Single protein]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Edwards, A M.]]
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</jmolCheckbox>
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[[Category: Evdokimova, E.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3brq ConSurf].
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[[Category: Joachimiak, A.]]
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<div style="clear:both"></div>
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[[Category: Kagan, O.]]
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__TOC__
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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</StructureSection>
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[[Category: Osipiuk, J.]]
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[[Category: Ecoli]]
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[[Category: Savchenko, A.]]
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[[Category: Large Structures]]
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[[Category: Singer, A U.]]
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[[Category: Edwards, A M]]
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[[Category: dna-binding]]
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[[Category: Evdokimova, E]]
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[[Category: mcsg]]
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[[Category: Joachimiak, A]]
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[[Category: midwest center for structural genomic]]
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[[Category: Kagan, O]]
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[[Category: protein structure initiative]]
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[[Category: Structural genomic]]
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[[Category: psi-2]]
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[[Category: Osipiuk, J]]
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[[Category: structural genomic]]
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[[Category: Savchenko, A]]
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[[Category: transcription regulation]]
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[[Category: Singer, A U]]
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[[Category: transcription regulator]]
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[[Category: Dna-binding]]
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[[Category: transcriptional repressor structure escherichia coli]]
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[[Category: Mcsg]]
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[[Category: PSI, Protein structure initiative]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:28:32 2008''
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[[Category: Transcription regulation]]
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[[Category: Transcription regulator]]
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[[Category: Transcriptional repressor structure escherichia coli]]

Current revision

Crystal structure of the Escherichia coli transcriptional repressor ascG

PDB ID 3brq

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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